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New method to detect organic nanoparticles in live tissue

机译:检测活组织中有机纳米颗粒的新方法

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摘要

In recent years, infiltrating materials into the human body has become a great challenge many researches are facing. In medicine and cosmetics today, there are materials which are administrated to patients by injection only. The main challenge with topical medication is penetrating the skin barrier. The skin is an effective barrier between the body and the outside environment, which prevents foreign materials entering the body easily. However, reducing the size of the desired materials might help their skin penetration ability. Recently nanoparticles (NPs) are being evaluated for use in many fields like chemistry, biology, medicine, physics and optics. The technique used in this work for forming organic NPs (ONPs) is the application of sonic waves to an aqueous solution, known as sonochemistry. To investigate the physical penetration depth of ONPs into the human body, we first developed a novel optical technique for detecting NPs within tissues. The detection of NPs is done by the extraction and investigation of the reemitted light phase.
机译:近年来,将材料渗透到人体中已成为许多研究面临的巨大挑战。在当今的药物和化妆品中,有些材料只能通过注射给药。局部用药的主要挑战是穿透皮肤屏障。皮肤是人体与外界环境之间的有效屏障,可防止异物轻易进入人体。但是,减小所需材料的尺寸可能有助于其渗透皮肤的能力。最近,纳米颗粒(NPs)正在评估用于许多领域,例如化学,生物学,医学,物理学和光学。这项工作中用于形成有机NP(ONP)的技术是将声波施加到水溶液中,称为声化学。为了研究ONP进入人体的物理渗透深度,我们首先开发了一种新颖的光学技术来检测组织中的NP。 NP的检测是通过提取和研究重新发射的光相来完成的。

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