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Preliminary Studies Regarding the Behaviour of New Titanium Implants

机译：关于新型钛植入物行为的初步研究

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摘要

This paper presents a study concerning a new titanium-based product reached by the specific techniques of powder metallurgy. The product was tested in vitro to corrosion in artificial saliva and in vivo by biological inocuity on sheep and rats for biocompatibility. The chemical composition of artificial saliva solutions used for general corrosion tests were: Fusayama solution; Carter solution; Ericsson solution; Hank solution; Ringer solution. The exposure length was 48, 720, 1440 and 2784 hours. On the sheep, six titanium implants of purity 99.89%, sintered with microporosities and nanoporosities at the surface were administered. Function of implant location, three cm incisions in the skin was made in the following regions: retroscapular for subcutaneous implants, in the tibial diaphysis for the subperiostal implant and in the Latimus Dorsi region for the intramuscular implant. Three different lots of Wistar breed rats were used; the sintered 3.5/1.5 cm titanium implants were placed subcutaneously and intermuscles. Parameters of descriptive statistics were used to assess inflammatory reaction.
机译：本文介绍了一种通过粉末冶金的特定技术获得的新型钛基产品的研究。通过对绵羊和大鼠进行生物接种，对产品在体外对人造唾液的腐蚀进行了体内和动物的生物相容性测试。用于一般腐蚀测试的人工唾液溶液的化学成分为：Fusayama溶液；卡特解决方案；爱立信解决方案；汉克解决方案；林格液。曝光时间为48、720、1440和2784小时。在绵羊上，施用了六种纯度为99.89％的钛植入物，这些植入物在表面烧结有微孔和纳米孔。在以下区域进行植入物定位的功能，在皮肤上切开三厘米的切口：用于皮下植入物的肩s骨后部，用于骨膜下植入物的胫骨骨干以及用于肌肉内植入物的Latimus Dorsi区域。使用了三批不同的Wistar品种大鼠。将烧结的3.5 / 1.5 cm钛植入物置于皮下和肌间。描述性统计参数用于评估炎症反应。

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