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Antioxidative and Antiinflammatory Activities of the Chloroform Extract of Ganoderma lucidum Found in South India

机译:印度南部发现的灵芝叶绿素提取物的抗氧化和抗炎活性

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Antioxidative and anti-inflammatory activities of Ganoderma lucidum (Curt.: Fr.) P. Karst. (Aphyllophoromycetideae) from tropical South India were investigated. The chloroform extract of the mushroom showed marked free radical scavenging activities. The anti-inflammatory activity of the extract at concentrations of 100 and 50 mg/kg was evaluated in carrageenan induced acute and formalin induced chronic inflammatory models in mice. The extract showed remarkable antiinflammatory activity in both models, comparable to the standard reference drug diclofenac. The results suggest that anti-inflammatory activity of the chloroform extract of G. lucidum is possibly attributed to its free radical scavenging properties. This study also reveals the potent therapeutic uses of G. lucidum from South India.
机译:灵芝的抗氧化和抗炎活性。考察了来自印度南部热带地区的(Aphyllophoromycetideae)。蘑菇的氯仿提取物具有明显的清除自由基活性。在角叉菜胶诱导的急性和福尔马林诱导的慢性小鼠炎症模型中评估了提取物在100和50 mg / kg浓度下的抗炎活性。该提取物在两个模型中均显示出显着的抗炎活性,与标准参考药物双氯芬酸相当。结果表明,灵芝的氯仿提取物的​​抗炎活性可能归因于其自由基清除特性。这项研究还揭示了来自南印度的灵芝的有效治疗用途。

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