Undifferentiated Marrow Stromal Cells Lose Their Osteogenic Capability After Exposure to Polymethylmethacrylate Particles in a Non-Osteogenic Environment

机译：在非成骨环境中暴露于聚甲基丙烯酸甲酯颗粒后，未分化的骨髓基质细胞丧失了成骨能力

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This study demonstrates that PMMA particles deprive bone marrow stem cells and osteoprogenitors in non-osteogenic medium of their ability to subsequently differentiate into osteoblasts after exposure to osteogenic factors in a particle-free environment. The inhibitory effects on differentiation are sustained even after particles are removed from culture.

机译：这项研究表明，PMMA颗粒剥夺了非成骨培养基中的骨髓干细胞和骨祖细胞，使其在无颗粒环境中暴露于成骨因子后能够分化为成骨细胞的能力。即使从培养物中除去颗粒，对分化的抑制作用仍然持续。

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来源
《Society for Biomaterials Transaction of the 31st Annual Meeting vol.XXIX pt.2》|2006年|P.566|共1页
会议地点 PittsburghPA(US)
作者
Chiu R; Ma T; Smith RL; Goodman SB;
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Stanford University School of Medicine, Stanford, CA;

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原文格式 PDF
正文语种 eng
中图分类生物材料学;
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专利

1. Dexamethasone Regulates EphA5, a Potential Inhibitory Factor with Osteogenic Capability of Human Bone Marrow Stromal Cells [J] . Yamada Tsuyoshi, Yoshii Toshitaka, Yasuda Hiroaki, Stem cells international . 2016,第4期

机译：地塞米松调节Epha5，具有人骨髓基质细胞的成骨能力的潜在抑制因子
2. After repeated division, bone marrow stromal cells express inhibitory factors with osteogenic capabilities, and EphA5 is a primary candidate [J] . Tsuyoshi Yamada, Masato Yuasa, Tomokazu Masaoka, Bone . 2014,第2期

机译：重复分裂后，骨髓基质细胞表达具有成骨能力的抑制因子，而EphA5是主要候选对象
3. After repeated division, bone marrow stromal cells express inhibitory factors with osteogenic capabilities, and EphA5 is a primary candidate [J] . Tsuyoshi Yamada, Masato Yuasa, Tomokazu Masaoka, Bone . 2013,第2期

机译：经过重复分裂后，骨髓基质细胞表达抑制因素具有成骨能力，而Epha5是主要候选者
4. Undifferentiated Marrow Stromal Cells Lose Their Osteogenic Capability After Exposure to Polymethylmethacrylate Particles in a Non-Osteogenic Environment [C] . Chiu R, Ma T, Smith RL, Society for Biomaterials Transaction of the 31st Annual Meeting vol.XXIX pt.2 . 2006

机译：在非成骨环境中暴露于聚甲基丙烯酸甲酯颗粒后，未分化的骨髓基质细胞丧失了成骨能力
5. Bionanoparticles as viable substrates to promote osteogenic differentiation of bone marrow stromal cells. [D] . Kaur, Gagandeep. 2010

机译：离子纳米颗粒作为可活的底物，可促进骨髓基质细胞的成骨分化。
6. Dexamethasone Regulates EphA5 a Potential Inhibitory Factor with Osteogenic Capability of Human Bone Marrow Stromal Cells [O] . Tsuyoshi Yamada, Toshitaka Yoshii, Hiroaki Yasuda, 2016

机译：地塞米松调节EphA5一种具有潜在成骨能力的人骨髓基质细胞成骨能力的抑制因子。
7. After repeated division, bone marrow stromal cells express inhibitory factors with osteogenic capabilities, and EphA5 is a primary candidate [O] . Tsuyoshi Yamada, Masato Yuasa, Tomokazu Masaoka, 2013

机译：经过重复分裂后，骨髓基质细胞表达抑制因素具有成骨能力，而Epha5是主要候选者

Undifferentiated Marrow Stromal Cells Lose Their Osteogenic Capability After Exposure to Polymethylmethacrylate Particles in a Non-Osteogenic Environment

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