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首页> 外文会议>Sol-Gel Methods for Materials Processing: Focusing on Materials for Pollution Control, Water Purification, and Soil Remediation >ORGANIC-INORGANIC HYBRID NANOMATERIALS WITH OPTICAL PROPERTIES FOR USE IN MEDICAL APPLICATIONS
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ORGANIC-INORGANIC HYBRID NANOMATERIALS WITH OPTICAL PROPERTIES FOR USE IN MEDICAL APPLICATIONS

机译：具有光学特性的有机-无机杂化纳米材料，用于医疗应用

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摘要

The tremendous developments of materials with fine tuning of the composition, shape, size and chemical functionalities at the nanometre scale has opened a wide range of applications in medicine. An overview of hybrid nano-materials for applications in biological environment will be presented. The use of functional particles for medical imaging and therapy will be especially discussed. These functional systems usually require combination of different properties such as luminescence (imaging) or molecular recognition (targeting) and non-linear optical properties (therapy), together with size/shape control and biocompatibility (cells diffusion, solubility, biochemical stability). For example series of hybrid metal or oxide nanoparticles can be prepared for medical imaging. Some of them are already commercially available. The most recent work in this field will be presented and the future developments will be discussed. For example one can expect to combine several imaging techniques (multimodal contrast agents) or imaging and therapy in the same nanocomposite. The use of hybrid systems combining inorganic (metal or oxide) with their organic counterparts shows the most promising routes towards such applications in biological environment. New trends in the field of phototherapy will be discussed.
机译：在纳米级对组成，形状，尺寸和化学功能进行微调的材料的巨大发展已经在医学领域中开辟了广泛的应用。将概述在生物环境中应用的杂化纳米材料。将特别讨论功能性颗粒在医学成像和治疗中的用途。这些功能系统通常需要结合不同的特性，例如发光（成像）或分子识别（靶向）和非线性光学特性（治疗），以及尺寸/形状控制和生物相容性（细胞扩散，溶解度，生化稳定性）。例如，可以制备一系列杂化金属或氧化物纳米颗粒用于医学成像。其中一些已经可以商业获得。将介绍该领域的最新工作，并讨论未来的发展。例如，可以期望在同一纳米复合材料中结合多种成像技术（多峰造影剂）或成像与治疗。结合使用无机（金属或氧化物）与有机物的混合体系显示出在生物环境中实现此类应用的最有希望的途径。将讨论光疗领域的新趋势。

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