SYNTHESIS AND CHARACTERIZATION OF A NOVEL BIODEGRADABLE AMPHIPHILIC MPEG-DENDRITIC BLOCK COPOLYMER CONTAINING (GLYCOLIC ACID)-ALT-(LACTIC ACID) OLIGOMER AND GLYCEROL

机译：含（乙醇酸）-ALT-（乳酸）低聚物和甘油的新型生物可降解两亲性MPEG-树突嵌段共聚物的合成与表征

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摘要

The design and synthesis of a novel biodegradable amphiphilic MPEG-dendritic block copolymer containing (glycolic acid)-alt-(lactic acid) oligomers and glycerol with potential applications in drug delivery is described. Their structures are confirmed by 1H NMR spectra, and their molecular weight distributions are measured by GPC.

机译：描述了一种新型的可生物降解的两亲性MPEG-树状嵌段共聚物的设计和合成，该共聚物含有（乙醇酸）-alt-（乳酸）低聚物和甘油，在药物递送中具有潜在的应用。它们的结构通过1 H NMR光谱证实，并且其分子量分布通过GPC测量。

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来源
《Symposium on innovative polymers for controlled delivery: Abstract book.》|2010年|p.593-595|共3页
会议地点 Suzhou(CN);Suzhou(CN)
作者
Jianwei Jiang; Li Zhang; Miao Wu; Xuefei Zhang;
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作者单位

Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education,Key Laboratory of Advanced Functional Polymeric Materials of College of Hunan Province, and Key Laboratory of Polymeric Materials Application Technology of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan 411105, China;

Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education,Key Laboratory of Advanced Functional Polymeric Materials of College of Hunan Province, and Key Laboratory of Polymeric Materials Application Technology of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan 411105, China;

Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education,Key Laboratory of Advanced Function;

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原文格式 PDF
正文语种 eng
中图分类生物材料学;生物材料学;
关键词
dendrimer; oligomer; glycerol; biodegradable;

机译：树状大分子;低聚物;甘油;可生物降解;

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专利

1. Synthesis, characterization, and drug delivery of amphiphilic poly{(lactic acid)-co-[(glycolic acid)-alt-(L-glutamic acid)]}-g-poly(ethylene glycol) [J] . Zuxiao Yu, Bin He, Chunyan Long, Macromolecular Research . 2012,第3期

机译：两亲性聚{（乳酸）-co-[[乙醇酸）-alt-（L-谷氨酸）]}-g-聚乙二醇的合成，表征和药物传递
2. Synthesis, Characterization, and Drug Delivery of Amphiphilic Poly{(lactic acid)-co-[(glycolic acid)-alt-(L-glutamic acid)]}-g-Poly(ethylene glycol) [J] . Zuxiao Yu, Bin He, Chunyan Long Macromolecular Research . 2012,第3期

机译：两亲性聚{（乳酸）-co-[[乙醇酸）-alt-（L-谷氨酸）]}-g-聚（乙二醇）的合成，表征和药物传递
3. Synthesis and characterization of a series of biodegradable and biocompatible PEG-supported poly(lactic-ran-glycolic acid) amphiphilic barbell-like copolymers [J] . Lu DD, Yuan JC, Li HG, Journal of Polymer Science, Part A. Polymer Chemistry . 2008,第11期

机译：一系列可生物降解和生物相容性的PEG负载的聚乳酸-乙醇酸两亲性杠铃状共聚物的合成与表征
4. SYNTHESIS AND CHARACTERIZATION OF A NOVEL BIODEGRADABLE AMPHIPHILIC MPEG-DENDRITIC BLOCK COPOLYMER CONTAINING (GLYCOLIC ACID)-ALT-(LACTIC ACID) OLIGOMER AND GLYCEROL [C] . Jianwei Jiang, Li Zhang, Miao Wu, Symposium on innovative polymers for controlled delivery . 2010

机译：一种含有（乙醇酸） - （乳酸）低聚物和甘油的新型可生物降解两亲物质MPEG-树突嵌段共聚物的合成与表征
5. Synthesis and Characterization of Silicate Ester Prodrugs and Poly(ethylene glycol)-b-poly(lactic-co-glycolic acid) Block Copolymers for Formulation into Prodrug-Loaded Nanoparticles. [D] . Wohl, Adam Richard. 2012

机译：硅酸酯酯前药和聚（乙二醇）-b-聚（乳酸-共-乙醇酸）嵌段共聚物的合成和表征，用于配制成载有前药的纳米颗粒。
6. Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid) [O] . Tao Yu, Ying-Ying Wang, Ming Yang, -1

机译：由聚乙二醇和聚（乳酸 - 共乙醇酸）的二嵌段共聚物组成的可生物降解的粘液渗透纳米颗粒
7. Mass Spectrometry-Based Analytical Strategy for Comprehensive Molecular Characterization of Biodegradable Poly(lactic-co-glycolic Acid) Copolymers [O] . -1

机译：基于质谱的可生物降解聚（乳酸 - 共乙醇酸）共聚物的综合分子表征分析策略
8. Synthesis of Poly(Lactoylglycolate): An Alternating Copolymer of Lactic and Glycolic Acids [R] . Ibay, A. C. 1987

机译：聚（乳酸乙醇酸酯）的合成：乳酸和乙醇酸的交替共聚物

SYNTHESIS AND CHARACTERIZATION OF A NOVEL BIODEGRADABLE AMPHIPHILIC MPEG-DENDRITIC BLOCK COPOLYMER CONTAINING (GLYCOLIC ACID)-ALT-(LACTIC ACID) OLIGOMER AND GLYCEROL

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