The work takes into consideration the in-vivo degradative aspects of three different glasses, showing some aspects of their bioactivity. Sterilized granules of Bioglass, S53P4 and A-WG glass granules were implanted in rabbit dorsal muscles and in sheep's mandible. After 60 days of implantation, the materials with the living tissues were explanted, embedded in PPMA and sectioned for the histologic and scanning electron microscopic observations. Elemental microanalyses with an Energy ispersive System were carried out to check the degradation of the materials through the topographic distribution of the elements. The three different glasses exhibited different states of degradation with differnet interactions with the soft and hard tissues for the same implatation tissues.
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