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INFLUENCE OF PROCESS PARAMETERS ON THE PARTICLE SURFACE STRUCTURE IN FLUIDIZED BED SPRAY GRANULATION

机译：流化床喷雾造粒过程参数对颗粒表面结构的影响

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Fluidized bed spray granulation is an important process for the formulation of a solid from a liquid starting material.The property of the produced granule like particle structure is depending on the chosen process parameters.Especially in pharmaceutics and food industry specific standards were posed to the granule surface.Depending on the application,the granules should dissolve rapidly or release over a longer period of time the active ingredient.These require differently structured surfaces.As part of this work model substances were used to investigate the influence of different spraying rates and temperatures on the formation of granule surface structures.

机译：流化床喷雾制粒是从液体原料制备固体的重要过程，所制得的颗粒的性质如颗粒结构取决于所选的工艺参数，特别是在制药和食品工业中，对颗粒提出了特定的标准根据用途，颗粒应迅速溶解或在较长的时间内释放出活性成分，这些颗粒需要结构不同的表面。作为该工作模型的一部分，物质被用来研究不同的喷涂速率和温度对颗粒的影响。颗粒表面结构的形成。

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来源
《The 18th international drying symposium》|2012年|1-6|共6页
会议地点 Xiamen(CN)
作者
T.Hoffmann; M.Peglow; E.Tsotsas;
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作者单位

NaWiTec,Thermal Process Engineering,Otto-von-Guericke University Magdeburg Universit(a)tsplatz 2,Magdeburg,D-39106,Germany;

NaWiTec,Thermal Process Engineering,Otto-von-Guericke University Magdeburg Universit(a)tsplatz 2,Magdeburg,D-39106,Germany;

NaWiTec,Thermal Process Engineering,Otto-von-Guericke University Magdeburg Universit(a)tsplatz 2,Magdeburg,D-39106,Germany;

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原文格式 PDF
正文语种 eng
中图分类空气处理;
关键词
fluidized beds; particle surface structure; spray granulation process;

机译：流化床;颗粒表面结构;喷雾造粒;

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专利

1. Influence of separation properties and processing strategies on product characteristics in continuous fluidized bed spray granulation [J] . Mueller Daniel, Bueck Andreas, Tsotsas Evangelos Powder Technology: An International Journal on the Science and Technology of Wet and Dry Particulate Systems . 2019,第期

机译：分离特性及加工策略对连续流化床喷涂造粒产品特性的影响
2. Influence of process conditions on the product Cheat tar properties in a continuous fluidized bed spray granulation process [J] . Diez E., Meyer K., Bueck A., Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers . 2018,第期

机译：工艺条件对连续流化床喷涂造粒工艺产品作弊焦油性能的影响
3. Influence of process variable and physicochemical properties on the granulation mechanism of mannitol in a fluid bed top spray granulator. [J] . Bouffard J, Kaster M, Dumont H Drug development and industrial pharmacy . 2005,第9期

机译：工艺变量和理化性质对流化床顶部喷雾制粒机中甘露醇造粒机理的影响。
4. INFLUENCE OF PROCESS PARAMETERS ON THE PARTICLE SURFACE STRUCTURE IN FLUIDIZED BED SPRAY GRANULATION [C] . T.Hoffmann, M.Peglow, E.Tsotsas International drying symposium . 2012

机译：工艺参数对流化床喷涂颗粒颗粒表面结构的影响
5. A numerical study of cohesive and non-cohesive particles in a bottom spray fluidized bed using fully coupled CFD-DEM simulations. [D] . Adepu, Manogna. 2015

机译：使用完全耦合的CFD-DEM模拟对底部喷雾流化床中内聚和非内聚颗粒的数值研究。
6. Influence of Formulation Parameters on Redispersibility of Naproxen Nanoparticles from Granules Produced in a Fluidized Bed Process [O] . Martin Wewers, Stefan Czyz, Jan Henrik Finke, 2020

机译：配方参数对流化床工艺生产的颗粒萘普生纳米粒再分散性的影响
7. Data-Driven Model-Free Adaptive Control of Particle Quality in Drug Development Phase of Spray Fluidized-Bed Granulation Process [O] . Zhengsong Wang, Dakuo He, Xu Zhu, 2017

机译：喷雾流化床造粒工艺药发电阶段粒子质量的数据驱动的无模型自适应控制
8. Evaluation of Minimum-Fluidizing Velocity Correlations for Bed Particles Used in Fluidized-Bed Calcination Processes. [R] . Kirkbride, R. A. 1988

机译：流化床煅烧过程中床颗粒最小流化速度相关性评价。

INFLUENCE OF PROCESS PARAMETERS ON THE PARTICLE SURFACE STRUCTURE IN FLUIDIZED BED SPRAY GRANULATION

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