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Evaluating the Use of Patient-Reported Non-Routine Events in Pediatric and Radiation Oncology: A Pilot Study

机译:评价在小儿和放射肿瘤学中患者报告的非常规事件的使用:一项初步研究

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This prospective pilot study evaluated (1) the potential for collecting structured longitudinal data on patient-reported non-routine events (PNREs) (i.e., events that deviate from expected or optimal care) during pediatric and adult radiation cancer therapies and (2) the potential relationship between PNREs, Patient-Reported Outcomes Measures (PROMs), and unplanned treatment events (UTEs). Along with PNREs, data were collected on patient’s background, distress, quality of life, hospital system care experience rating, and treatment intensity, during a 3-month period; UTEs were retrospectively captured through review of patients’ records. Initial results suggest a relationship exists between both PNREs and safety-relevant PNREs with patient distress, quality of life, and care experience ratings. UTEs occurred more often in pediatric patients and were primarily related to patients’ underlying disease. This systems-safety approach to identifying at-risk points in treatment pathways has the potential to provide actionable information for the mitigation of shortcomings in cancer therapy.
机译:这项前瞻性先导研究评估了(1)在儿科和成人放射癌治疗期间收集有关患者报告的非常规事件(PNRE)(即,偏离预期或最佳护理的事件)的结构化纵向数据的潜力,以及(2) PNRE,患者报告的结果指标(PROM)和计划外的治疗事件(UTE)之间的潜在关系。与PNRE一起,在3个月的时间内收集了有关患者的背景,痛苦,生活质量,医院系统护理经验等级和治疗强度的数据;通过检查患者的记录来回顾性地记录UTE。初步结果表明,PNRE和与安全相关的PNRE与患者的痛苦,生活质量和护理经验等级之间存在关系。 UTE多发于儿科患者,并且主要与患者的基础疾病有关。这种系统安全的方法可识别治疗途径中的高风险点,具有为减轻癌症治疗中的缺点提供可行信息的潜力。

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    Center for Research and Innovation in Systems Safety, Vanderbilt University Medical Center (VUMC);

    Center for Research and Innovation in Systems Safety, Vanderbilt University Medical Center (VUMC),Vanderbilt Ingram Cancer Center;

    Vanderbilt Ingram Cancer Center;

    Vanderbilt Ingram Cancer Center;

    Vanderbilt Ingram Cancer Center;

    Department of Biostatistics, Vanderbilt University School of Medicine;

    Center for Research and Innovation in Systems Safety, Vanderbilt University Medical Center (VUMC);

    Center for Research and Innovation in Systems Safety, Vanderbilt University Medical Center (VUMC);

    Center for Research and Innovation in Systems Safety, Vanderbilt University Medical Center (VUMC);

    Center for Research and Innovation in Systems Safety, Vanderbilt University Medical Center (VUMC),Vanderbilt Ingram Cancer Center,VA Tennessee Valley Healthcare System;

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