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首页> 外文会议>Ultrasonic Imaging and Signal Processing; Progress in Biomedical Optics and Imaging; vol.8,no.32; Proceedings of SPIE-The International Society for Optical Engineering; vol.6513 >Ultrasound-only dosimetry for prostate brachytherapy: preliminary phantom results
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Ultrasound-only dosimetry for prostate brachytherapy: preliminary phantom results

机译：前列腺近距离放射疗法的仅超声剂量测定：初步幻像结果

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摘要

Accurate and fast seed localization plays a key role in computing dosimetry for prostate brachytherapy. Because transrectal ultrasound is the primary imaging modality providing the guidance for prostate brachytherapy, an ultrasound-only approach for dosimetry would offer many benefits. In this paper, we propose an ultrasound-only dosimetry solution, in which the brachytherapy seeds are located in reflected power images computed from ultrasonic radio frequency signals and the boundary of the prostate is delineated from B-mode TRUS and vibro-elastography images as the prostate is stiffer than the surrounding tissue. The location of the implanted seeds relative to the prostate boundary is thus obtained. As only one imaging modality, ultrasound, is used, image registration is easy to implement. A prostate phantom with seeds embedded within it was built to evaluate the proposed approach. To measure the seed localization accuracy in the reflected power images, the phantom was scanned by CT as well. Experimental results show that the implanted seeds can be successfully located in the reflected power images with high contrast and accuracy, and that the contour of the "prostate" can be detected in the ultrasound vibro-elastography images outside the shadow of the seeds.
机译：准确，快速的种子定位在计算前列腺癌近距离放射剂量中起着关键作用。由于经直肠超声是为前列腺近距离放射治疗提供指导的主要成像方式，因此仅采用超声的剂量学方法将带来许多好处。在本文中，我们提出了一种仅超声的剂量测定解决方案，其中，近距离放射治疗种子位于从超声射频信号计算出的反射功率图像中，而前列腺边界则从B型TRUS和振动弹力图图像中划出。前列腺比周围组织硬。由此获得相对于前列腺边界的植入种子的位置。由于仅使用一种超声成像方式，因此易于实现图像配准。构建了一个带有植入种子的前列腺模型，以评估所提出的方法。为了测量反射功率图像中的种子定位精度，还通过CT扫描了体模。实验结果表明，所植入的种子可以成功地以高对比度和准确度位于反射功率图像中，并且可以在种子阴影之外的超声振动弹力描记图像中检测到“前列腺”的轮廓。

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