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Cytokine Expression in Childhood Central Nervous System Tumors

机译:细胞因子在儿童中枢神经系统肿瘤中的表达

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摘要

Cytokines are extensively studied small molecules, but their role in childhood CNS neoplasias is still to be elucidated. CNS tumors are of major interest because even if the outcome is favorable, the side-effects stemming from the nature of the disease are devastating. Even after successful treatment, side-effects may influence the quality of life of the patient. This makes the discovery of new prognostic and therapeutic factors more imperative. In the current report, ten cytokines have been chosen to be further studied, which were: EGF, Eotaxin, FGF2, FLT3 ligand, Fractalkine, IL-6, IL-8, MCP-1, TNF-alpha and VEGF.
机译:细胞因子是广泛研究的小分子,但其在儿童中枢神经系统肿瘤形成中的作用尚待阐明。中枢神经系统肿瘤是主要关注的问题,因为即使结果令人满意,但由于疾病的性质所引起的副作用却具有破坏性。即使成功治疗后,副作用也可能影响患者的生活质量。这使得发现新的预后和治疗因素变得势在必行。在本报告中,已经选择了十种细胞因子进行进一步研究,它们是:EGF,嗜酸性粒细胞趋化因子,FGF2,FLT3配体,Fractalkine,IL-6,IL-8,MCP-1,TNF-α和VEGF。

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