ABBREVIATIONS
CHAPTER Ⅰ
1.1 Arsenic properties
1.2 Global Distribution of Arsenic
1.3 Route of Entry and Arsenic Metabolism
1.4 Arsenic Toxicity
1.4.1 Acute Arsenic Poisoning
1.4.2 Chronic Arsenic Poisoning
1.5 Epidemiological Studies on Health Effects of Arsenic
1.5.1 Epidemiological Study on Non-Cancerous Disease
1.6 The effect of Arsenic on Endocrine system
1.6.1. The effect of Arsenic on thyroid endocrine system
1.6.2 The effect of Arsenic on Gonadal endocrine system
1.6.3 The effect of Arsenic on Adrenal endocrine system
参考文献
Chapter Ⅱ The toxic effect of arsenic on developmental and growth of zebrafish at early life stage
2.1. Introduction
2.2. Materials and methods
2.2.1. Fish maintenance and embryo collection
2.2.2. Experimental design
2.2.3. Oxidative stress analysis
2.2.4. RNA isolation, cDNA synthesis for genes and Quantification of gene expression
2.2.5. Statistical analysis
2.3. Results and discussion
2.3.1 The survival and developmental performances of early life stage of zebrafish
2.3.2 SOD activity and mRNA transcriptional performances of zebrafish larvae
2.3.3 The impact of As on MDA contents of zebrafish larvae
2.3.4 The mRNA transcriptional levels of MT and HSP70 of zebrafish larvae
参考文献
Chapter Ⅲ The toxic effect of arsenic on endocrine system of zebrafish at early life stage
3.1. Introduction
3.2. Materials and methods
3.2.1. Fish maintenance and embryo collection
3.2.2. Experimental design
3.2.3. hormone extraction and measurement
3.2.5. Statistical analysis
3. 3. Results and discussion
3.3.2 The effect of AsⅢ on the cortisol levels
3.3.3 The effect of AsⅢ on the estroadiol and testosterone levels
参考文献
Chapter Ⅳ
4.0 Conclusion
致谢
声明
浙江师范大学;
