• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Dietary exposure, human body loadings, and health risk assessment of persistent organic pollutants at two major electronic waste recycling sites in China.
【24h】

Dietary exposure, human body loadings, and health risk assessment of persistent organic pollutants at two major electronic waste recycling sites in China.

机译：在中国两个主要电子废物回收站的膳食暴露，人体负荷和持久性有机污染物的健康风险评估。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Total diet studies, covering 9 major food groups (freshwater fish, marine fish, shellfish, meat, poultry, egg, viscera, vegetables, and cereal), were conducted in two major e-waste recycling sites (Guiyu and Taizhou) which are located at coastal areas and a reference site (Lin'an) which is located inland to investigate the human dietary exposure to PBDEs and DDTs. The dietary intake of PBDEs by Guiyu women was 931 772 ng/kg bw/day of which the intake of BDE-47 was 584 ng/kg bw/day exceeding the US EPA's reference dose (100 ng/kg/day). The intakes of PBDEs by Taizhou and Lin'an mothers were 44.7 +/- 26.3 and 1.94 +/- 0.86 ng/kg bw/day, respectively. Seafood, particularly freshwater fish, was the main dietary source of PBDEs in Guiyu and Taizhou, accounted for 88-98%, while pork (41%) was the main contributor in Lin'an. The levels of PBDEs in river fish from Guiyu (76.1-11353 ng/g wet wt) were the highest throughout the world. The exposure to DDTs through dietary intake in Taizhou was estimated at 52.1 +/- 49.5 ng/kg bw/day, dominated by viscera (34%) and seafood (38%) (total 72%). The value for Guiyu was 31.5 +/- 34.8 ng/kg bw/day, largely contributed by vegetables (29%), seafood (24%), and poultry (34%) (total 87%), while that for Lin'an was estimated at 13.0 +/- 6.51 ng/kg bw/day, dominated by pork (41%), poultry (22%) and vegetables (13%) (total 76%). The estimated daily intakes of DDTs of the study sites were far below the JMPR Provisional Tolerable Daily Intake (10,000 ng/kg bw/day).;Levels of PCDD/Fs in wild freshwater fish from Guiyu (4.64 +/- 2.69 pg WHO-TEQ/g wet wt) were up to 12 and 107 times higher than Taizhou group (0.90 0.38 pg WHO-TEQ/g wet wt) and Lin'an market fish (0.08 +/- 0.01 pg WHO-TEQ/g wet wt) respectively and were at the high end of the worldwide range. The exposure to PCDD/Fs via fish consumption by Guiyu women (1.95 +/- 1.25 pg WHO-TEQ/kg bw/day) was at least 5 times higher than that by Taizhou (0.37 +/- 0.36 pg WHO-TEQ/kg bw/day) and Lin'an women (0.03 +/- 0.03 pg WHO-TEQ/kg bw/day). The maximum intakes of PCDD/Fs in Guiyu (4.31 pg WHO-TEQ/kg bw/day) exceeded the higher end of the WHO Tolerable Daily Intake (1-4 pg WHO-TEQ/kg bw/day). The results of dioxin-like activities of fish samples determined by H4IIE-luc cell bioassay demonstrated that H4IIE-luc cell bioassay was a very sensitive, cost-effective screening tool for assessing the overall dioxin-like toxicity in the samples.;Milk, placenta and hair were collected to determine the body burdens of PCDD/Fs, PBDEs and DDTs of lactating women at the study sites. Concentrations of PCDD/Fs in human milk (21.0 +/- 13.8 pg WHO-TEQ/g fat), placenta (31.2 +/- 15.7 pg WHO-TEQ/g fat) and hair (33.8 +/- 17.7 pg WHO-TEQ/g dry wt) from Taizhou were significantly higher than those from Lin'an (milk: 9.35 +/- 7.39 pg WHO-TEQ/g fat; placenta: 11.9 +/- 7.05 pg WHO-TEQ/g fat; and hair: 5.59 +/- 4.36 pg WHO-TEQ/g dry wt) and were comparatively higher than other studies. The daily intakes of PCDD/Fs by Taizhou and Lin'an infants via breast-feeding were estimated at 102.98 +/- 67.65 and 45.83 +/- 36.22 pg-TEQ/kg body wt/day, respectively. Both exceeded the WHO Tolerable Daily Intake by at least 25 and 11 times.;The Sigma7PBDE levels in milk samples from Guiyu (94.1 +/- 86.4 ng/g fat) and Taizhou (70.7 +/- 114 ng/g fat) were significantly higher than those from Lin'an (1.43 0.81 ng/g fat) and topped the list of the nationwide and worldwide figures. The total PBDE levels of placenta (19.5 +/- 30.0 ng/g fat) and hair (110 +/- 210 ng/g dry wt) from Taizhou exceeded those from Lin'an (placenta: 1.02 +/- 0.36; hair 3.57 +/- 2.03 ng/g dry wt) by at least 19 times. Levels of DDTs in the body of donors from Guiyu (milk: 305 +/- 109 ng/g fat) and Taizhou (milk: 360 +/- 319 ng/g fat; placenta: 122 +/- 109 ng/g fat; hair: 79.9 215 ng/g dry wt) were also significantly higher than those from Lin'an.;The present study revealed that food and human specimens collected from the e-waste recycling sites were more contaminated with PCDD/Fs and PBDEs than the reference site because of the uncontrolled e-waste recycling operations which led to high background levels. Such differences were also observed in the case of DDTs, due to greater application of DDT at the coastal areas. The elevated levels of PCDD/Fs and PBDEs in food and human body observed in Guiyu and Taizhou may impose health implications for the next generation. (Abstract shortened by UMI.)
机译：在两个主要的电子废物回收站（桂屿和台州）进行了总饮食研究，涵盖9种主要食品类别（淡水鱼，海鱼，贝类，肉，家禽，蛋，内脏，蔬菜和谷物）在沿海地区和内陆一个参考点（临安）进行调查，以研究人类饮食中多溴二苯醚和滴滴涕的暴露情况。贵屿妇女的饮食中多溴二苯醚的饮食摄入量为931 772 ng / kg bw /天，其中BDE-47的摄入量为584 ng / kg bw /天，超过了美国EPA的参考剂量（100 ng / kg /天）。泰州和临安母亲的PBDEs摄入量分别为44.7 +/- 26.3和1.94 +/- 0.86 ng / kg bw /天。海鲜，特别是淡水鱼，是贵屿和台州多溴联苯醚的主要膳食来源，占88-98％，而猪肉（41％）是临安的主要膳食来源。贵屿河鱼中的多溴二苯醚含量（76.1-11353 ng / g湿重）是世界最高的。在台州，通过饮食摄入的滴滴涕暴露量估计为52.1 +/- 49.5 ng / kg bw /天，主要是内脏（34％）和海鲜（38％）（总计72％）。桂yu的价值为31.5 +/- 34.8 ng / kg体重/天，主要由蔬菜（29％），海鲜（24％）和家禽（34％）（总计87％）贡献，而临安的价值估计为13.0 +/- 6.51 ng / kg bw /天，主要是猪肉（41％），家禽（22％）和蔬菜（13％）（总计76％）。研究地点的滴滴涕估计每日摄入量远低于JMPR临时可耐受的每日摄入量（10,000 ng / kg体重/天）。贵屿野生淡水鱼中PCDD / Fs的水平（4.64 +/- 2.69 pg世卫组织TEQ / g湿重）分别比泰州组（0.90 0.38 pg WHO-TEQ / g湿重）和临安市集鱼（0.08 +/- 0.01 pg WHO-TEQ / g湿重）高12倍和107倍分别处于全球范围的高端。贵屿妇女通过食用鱼类对PCDD / Fs的暴露量（1.95 +/- 1.25 pg WHO-TEQ / kg bw /天）至少比泰州（0.37 +/- 0.36 pg WHO-TEQ / kg）高五倍bw / day）和临安妇女（0.03 +/- 0.03 pg WHO-TEQ / kg bw / day）。贵屿的PCDD / Fs最大摄入量（4.31 pg WHO-TEQ / kg bw /天）超过了WHO每日容许摄入量的上限（1-4 pg WHO-TEQ / kg bw /天）。通过H4IIE-luc细胞生物测定法测定的鱼样品中二恶英样活性的结果表明，H4IIE-luc细胞生物测定法是评估样品中总体二恶英样毒性的非常灵敏，具有成本效益的筛选工具。收集头发和头发以确定研究地点的哺乳期妇女PCDD / Fs，PBDEs和DDT的身体负担。人乳（21.0 +/- 13.8 pg WHO-TEQ / g脂肪），胎盘（31.2 +/- 15.7 pg WHO-TEQ / g脂肪）和头发（33.8 +/- 17.7 pg WHO-TEQ）中PCDD / Fs的浓度泰州的每克干重/ g显着高于临安（牛奶：9.35 +/- 7.39 pg WHO-TEQ / g脂肪；胎盘：11.9 +/- 7.05 pg WHO-TEQ / g脂肪；头发： 5.59 +/- 4.36 pg WHO-TEQ / g干重），相对高于其他研究。泰州和临安婴儿通过母乳喂养每日摄入的PCDD / Fs分别为102.98 +/- 67.65 pg-TEQ / kg体重/天，为45.83 +/- 36.22 pg-TEQ / kg体重/天。两者均超过了WHO耐受的每日摄入量至少25倍和11倍;贵屿（泰州）（94.1 +/- 86.4 ng / g脂肪）和泰州（70.7 +/- 114 ng / g脂肪）的牛奶样品中Sigma7PBDE含量显着高于临安的脂肪含量（1.43 0.81 ng / g脂肪），位居全国和全球数据之首。来自台州的胎盘和头发（干重110 +/- 210 ng / g）的多溴二苯醚总PBDE水平超过临安（胎盘：1.02 +/- 0.36；头发3.57） +/- 2.03 ng / g干重）至少19倍。贵屿（牛奶：305 +/- 109 ng / g脂肪）和台州（牛奶：360 +/- 319 ng / g脂肪；胎盘：122 +/- 109 ng / g脂肪；牛脂：122 +/- 109 ng / g脂肪；胎盘：122 +/- 109 ng / g脂肪；头发：79.9 215 ng / g干重）也显着高于临安市。;本研究表明，从电子废物回收地点收集的食物和人类标本比PC污染物更容易被PCDD / Fs和PBDEs污染。参考站点，因为电子垃圾回收操作不受控制，导致本底水平很高。由于在沿海地区更多地使用了滴滴涕，因此在滴滴涕中也观察到了这种差异。在贵屿和台州发现，食物和人体中PCDD / Fs和PBDEs含量升高，可能对下一代健康产生影响。 （摘要由UMI缩短。）

著录项

  • 作者

    Chan, Kit Yan.;

  • 作者单位

    Hong Kong Baptist University (Hong Kong).;

  • 授予单位 Hong Kong Baptist University (Hong Kong).;
  • 学科 Health Sciences Occupational Health and Safety.;Health Sciences Public Health.;Environmental Sciences.
  • 学位 Ph.D.
  • 年度 2008
  • 页码 326 p.
  • 总页数 326
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号