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High-performance dual-energy imaging with a flat-panel detector .

机译:带有平板探测器的高性能双能成像。

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摘要

Mounting evidence suggests that the superposition of anatomical clutter in x-ray chest radiography poses a major impediment to the detectability of subtle lung nodules. Through decomposition of projections acquired using different x-ray energy spectra, dual-energy (DE) imaging offers to dramatically improve lung nodule conspicuity. The development of a high-performance DE chest imaging system is reported, with design and implementation guided by fundamental imaging performance metrics. Analytical and experimental studies of imaging performance guided the optimization of key acquisition technique parameters, including x-ray filtration, allocation of dose between low- and high-energy projections, and peak-kilovoltage selection. To minimize anatomical misregistration between images, a cardiac gating system was designed and implemented to direct x-ray exposures to within the quiescent period of the heart cycle. The instrumentation and optimal imaging techniques have been incorporated in a DE imaging prototype system now deployed in a clinical study to evaluate the diagnostic performance of DE imaging.
机译:越来越多的证据表明,X线胸片中的解剖杂波叠加严重阻碍了细微肺结节的可检测性。通过分解使用不同X射线能谱获得的投影,双能(DE)成像可显着改善肺结节的醒目性。报告了高性能DE胸部成像系统的开发,其设计和实现均以基本成像性能指标为指导。成像性能的分析和实验研究指导了关键采集技术参数的优化,包括X射线过滤,低能和高能投影之间的剂量分配以及峰值千伏电压选择。为了最大程度地减少图像之间的解剖配准失调,设计并实施了心脏门控系统,以将X射线照射引导至心脏周期的静止期内。仪器和最佳成像技术已整合到DE成像原型系统中,该系统现已部署在临床研究中,以评估DE成像的诊断性能。

著录项

  • 作者

    Shkumat, Nicholas Andrew.;

  • 作者单位

    University of Toronto (Canada).;

  • 授予单位 University of Toronto (Canada).;
  • 学科 Biophysics Medical.
  • 学位 M.Sc.
  • 年度 2008
  • 页码 125 p.
  • 总页数 125
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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