• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文学位 >Central Lymph Node Dissection in Patients with Papillary Thyroid Cancer: A Population Level Analysis of 14,257 Cases.
【24h】

Central Lymph Node Dissection in Patients with Papillary Thyroid Cancer: A Population Level Analysis of 14,257 Cases.

机译：乳头状甲状腺癌患者的中央淋巴结清扫术：14,257例人群水平分析。

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The role of prophylactic central lymph node dissection (CLND) in patients with differentiated thyroid cancer has been controversial. This study analyzes the impact of patient demographic factors and tumor size on surgery with CLND in patients with papillary thyroid cancer (PTC) in the U.S.;All patients ≥ 18 with PTC and follicular variant-PTC, who underwent thyroidectomy with or without CLND in SEER, 2004-08, were included. Bivariate and multivariate analyses were performed to determine effects of patient demographic and clinical characteristics on the likelihood of undergoing CLND.;Of 14,257 patients in the study, 80.3% were women, 84.3% white, and the average age was 50.1 years. 79.6% had a total thyroidectomy, and 37.1% had a CLND. Bivariate analysis revealed that patients who were older, black, and from the South were less likely to undergo CLND (all p<. 001). Patients with T1 tumors were least likely to undergo CLND (36.6% compared to 57.2% of T4 tumors, p<. 01). 32.1% of patients with 2 cm had CLND, of which 3.6% (microPTC) and 8.8% (tumors 1-2cm) had positive nodes compared to 34.2% of patients with T4 tumors. From 2004 to 2008, there was an 18.3% increase in overall use of CLND. On multivariate analysis, younger age, female gender, white race, and Northeast region were independently associated with an increased likelihood of undergoing CLND. While the use of CLND has increased over time even in patients with T1 tumors, several demographic factors remain associated with lower likelihood of receiving CLND. This variation in practice suggests potential disparity in access and quality of surgical care for PTC in the U.S.
机译：预防性中央淋巴结清扫术（CLND）在分化型甲状腺癌患者中的作用一直存在争议。这项研究分析了美国乳头状甲状腺癌（PTC）患者的人口统计学因素和肿瘤大小对CLND手术的影响;所有≥18岁的PTC和滤泡变体PTC患者在SEER中接受或不进行CLND均行甲状腺切除术，2004-08年。进行了双因素和多因素分析，以确定患者的人口统计学和临床​​特征对接受CLND的可能性的影响。在研究的14257名患者中，女性为80.3％，白人为84.3％，平均年龄为50.1岁。甲状腺全切除术占79.6％，CLND占37.1％。双变量分析显示，年龄较大，黑人且来自南方的患者接受CLND的可能性较小（所有p <.001）。 T1肿瘤患者接受CLND的可能性最小（36.6％，而T4肿瘤为57.2％，p <0.01）。 32.1％的2 cm患者患有CLND，其中3.6％（microPTC）和8.8％（肿瘤1-2cm）具有阳性淋巴结转移，而T4肿瘤患者为34.2％。从2004年到2008年，CLND的整体使用量增长了18.3％。在多变量分析中，年龄，女性，白人，东北地区与年轻女性发生CLND的可能性增加独立相关。尽管即使在患有T1肿瘤的患者中，CLND的使用也随着时间而增加，但一些人口统计学因素仍然与接受CLND的可能性较低相关。在实践中的这种差异表明，在美国，PTC的手术治疗和质量可能存在差异。

著录项

  • 作者

    Enyioha, Chineme Ijeoma.;

  • 作者单位

    Yale University.;

  • 授予单位 Yale University.;
  • 学科 Health Sciences Medicine and Surgery.;Health Sciences Oncology.;Health Sciences Surgery.
  • 学位 M.D.
  • 年度 2013
  • 页码 52 p.
  • 总页数 52
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号