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首页> 外文学位 >A Novel, Non-Biological Clot Material for Simulating Mechanical Thrombectomy in Acute Ischemic Stroke.
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A Novel, Non-Biological Clot Material for Simulating Mechanical Thrombectomy in Acute Ischemic Stroke.

机译：一种新型的非生物凝块材料，用于模拟急性缺血性卒中的机械血栓切除术。

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摘要

Medical simulation technology is becoming more advanced and clinic-representative. Consequently, a shift in the initial training of residents away from the patients is beginning. Medical training for endovascular procedures is no different; simulators are becoming more popular and economical as alternatives to animal training. More recently, physical simulators that can provide superior haptic feedback of the endovascular procedures and devices are becoming available; this technology is especially useful for training physicians to perform interventional procedures for stroke treatment in the tortuous anatomy of the human cerebrovasculature. The novel clot material developed in this study was generated from Gak and Borax, and it was injected into a patient-representative, silicone vascular model to simulate acute ischemic stroke. The novel clot material was compared to clinically-retrieved clot, and it was determined that the novel clot material with a 4.5% Borax concentration was the softest and represented what physicians might expect clinically. A large vessel occlusion model was designed to simulate an embolism at the middle cerebral artery. The clot was injected into the patient-representative model using a 7F introducer, which provided the smallest clot that would cause an occlusion. The clot was successfully retrieved using a Solitaire FR Revascularization Device, and the simulation of a mechanical thrombectomy procedure in a tortuous, clinically-applicable vasculature was successfully performed.
机译：医学模拟技术正变得越来越先进，并在临床上具有代表性。因此，开始对住院医生进行远离患者的初始培训。血管内手术的医学培训没有什么不同。作为动物训练的替代方法，模拟器正变得越来越流行和经济。最近，可以提供血管内手术和设备的出色触觉反馈的物理模拟器已经面市。这项技术对于培训医师在人脑血管系统的弯曲解剖结构中进行中风治疗的介入程序特别有用。在这项研究中开发的新型凝块材料是由Gak和Borax产生的，并将其注射到以患者为代表的硅胶血管模型中以模拟急性缺血性中风。将这种新型凝块材料与经过临床处理的凝块进行了比较，确定具有4.5％硼砂浓度的新型凝块材料最软，并且代表了医生在临床上的期望。设计大血管闭塞模型以模拟大脑中动脉的栓塞。使用7F导引器将血凝块注射到患者代表模型中，该导引器可提供最小的血凝块，从而引起阻塞。使用Solitaire FR血运重建设备成功回收了血块，并成功地在曲折的临床可应用脉管系统中模拟了机械血栓切除术。

著录项

  • 作者

    Santore, Joseph.;

  • 作者单位

    State University of New York at Stony Brook.;

  • 授予单位 State University of New York at Stony Brook.;
  • 学科 Engineering Biomedical.;Biophysics Biomechanics.
  • 学位 M.S.
  • 年度 2013
  • 页码 82 p.
  • 总页数 82
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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