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Effectiveness of Continuous Glucose Monitoring in Children, Adolescents and Young Adults with Poorly Controlled Type 1 Diabetes.

机译:在儿童,青少年和年轻人中控制不佳的1型糖尿病的连续血糖监测的有效性。

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Background: Type 1 diabetes is the second most common chronic illness seen in children. Children, adolescents and young adults with type 1 diabetes are provided care in programs with diabetes educators, nurses, nurse practitioners, physicians, dietitians, and many other specialists. Even though children, adolescents and young adults receive care from many providers, their diabetes is often not in good control. In the last 10 years a new device called a continuous glucose monitor has been developed for use with people with diabetes. This new device documents the blood sugar levels in people with diabetes between finger stick blood sugar tests.;Objectives: This study utilized a newly developed investigational continuous glucose monitoring device in children, adolescents and young adults ages 7-21 who had very high blood sugars and a Hemoglobin A1c of 9% or greater. The rationale was that if the participants could see their blood sugars in between regular testing, it would help them to lower their blood sugars. The study used the Family Approach to Diabetes Management model to improve adherence to wearing the CGM monitor. The primary outcome of the study was to improve HbA1c by at least 0.5%. Secondary outcomes of the study included: adherence to wearing the continuous glucose monitor, adherence to blood sugar testing, decrease in hypoglycemia, and change in quality of life indicators.;Design: This study used a prospective, one group, pre and post-test pre experimental design, with a convenience sample of patients. The 12-week intervention tested the efficacy of a newly developed continuous glucose monitor on glycemic control. Participants were seen every four weeks during the study. At the baseline visit, demographic data were collected and participants completed the Quality of Life for Youth form. Patients and families were taught to use the continuous glucose monitor and the basic concepts of the Family Approach to Diabetes Management Model. Baseline HgA1c levels were determined, as well as reported and actual frequency of blood testing. Data collected at the subsequent visits included downloads from of the continuous glucose monitor, home finger stick blood glucose monitor and completion of a qualitative interview about experiences with the monitor use. In addition, data collected at the final study visit included collection of HbA1cs and completion of the Quality of Life for Youth forms.;Subjects: Thirty-three subjects enrolled in the study. Twenty-one (63.6%) completed the final study visit at 12 weeks. The mean age of the subjects was 15.57 years with a range of 11 to 20 years. Of the 21 that finished the study, 47.6% were male and 52.4% were female.;Results: There was a clinically and statistically significant improvement in HbA1c from baseline by 1.1095% (SD=1.9321) p=0.016. Fifteen of the participants (71.4%) had an improvement of greater than 0.5% in HbA1c. Participants wore the CGM monitor a mean of 51.1429 (SD=20.68543) days with a range of 21 to 81 days. For this study, wearing the monitor any part of the day was counted as one day. The participants wore the monitor a mean of 4.262 days a week. At the end of the study, two participants were identified as manipulating the CGM device and did not provide accurate finger stick blood glucoses to calibrate the monitor. The change in HbA1c was recalculated removing these participants from the analysis resulting in, a mean improvement of 1.4579% (SD=1.6711) p=0.001. While there were no significant differences in quality of life among the six subscales evaluated, there was a trend in improvement of areas of symptoms, treatment, parental issues, worry, and health. Data derived from qualitative interviews demonstrated an improved attitude among the participants and improved parent child interaction.;Conclusion: Continuous glucose monitoring with the Family Approach to Diabetes Management model was effective in improving glycemic control with children, adolescents and young adults with poorly controlled diabetes.
机译:背景:1型糖尿病是儿童中第二常见的慢性疾病。在糖尿病教育者,护士,执业护士,医师,营养师和许多其他专家的计划下,为患有1型糖尿病的儿童,青少年和年轻人提供了护理。即使儿童,青少年和年轻人得到了许多医疗机构的护理,但他们的糖尿病往往得不到控制。在过去的十年中,已经开发出一种新的设备,称为连续血糖监测仪,可用于糖尿病患者。该新设备记录了指尖血糖测试之间糖尿病患者的血糖水平。;目的:本研究利用一种新开发的连续性血糖监测设备,用于血糖水平很高的儿童,青少年和7-21岁的年轻人血红蛋白A1c为9%或更高。理由是,如果参与者可以在定期测试之间看到自己的血糖,那将有助于他们降低血糖。该研究使用“家庭糖尿病管理方法”模型来提高对佩戴CGM监护仪的依从性。该研究的主要结果是将HbA1c改善至少0.5%。研究的次要结果包括:坚持佩戴连续血糖监测仪,坚持血糖检测,降低低血糖症以及生活质量指标的变化。设计:本研究采用前瞻性,一组,前测和后测预先进行实验设计,并为患者提供方便的样本。为期12周的干预措施测试了新开发的连续血糖监测仪对血糖控制的功效。在研究过程中,每四周会见一次参与者。在基线访问时,收集了人口统计数据,参与者填写了《青年生活质量》表格。教导患者和家属使用连续血糖监测仪和“家庭糖尿病管理模型方法”的基本概念。确定基线HgA1c水平,以及报告的和实际的血液检测频率。在随后的访问中收集的数据包括从连续血糖监测仪,家用指尖血糖监测仪下载以及完成有关监测仪使用经验的定性访谈。此外,在最后一次研究访问中收集的数据包括HbA1cs的收集和青年生活质量表格的填写。受试者:33名受试者参加了研究。 21周(63.6%)完成了最后的研究访问。受试者的平均年龄为15.57岁,范围为11至20岁。在完成研究的21个研究中,男性占47.6%,女性占52.4%。;结果:HbA1c与基线相比在临床和统计学上有显着改善1.1095%(SD = 1.9321)p = 0.016。 15名参与者(71.4%)的HbA1c改善大于0.5%。参与者佩戴CGM监测仪的平均时间为51.1429(SD = 20.68543)天,范围为21至81天。在本研究中,一天中任何时候佩戴显示器都被视为一天。参与者平均每周佩戴4.262天。在研究结束时,有两名参与者被确认正在操纵CGM设备,但没有提供准确的指尖血糖来校准监护仪。重新计算了HbA1c的变化,从分析中删除了这些参与者,导致平均改善1.4579%(SD = 1.6711)p = 0.001。在所评估的六个分量表中,生活质量没有显着差异,但在症状,治疗,父母问题,忧虑和健康方面有所改善。从定性访谈中获得的数据表明,参与者之间的态度有所改善,亲子互动也得到了改善。;结论:糖尿病家庭管理模式的持续血糖监测有效改善了儿童,青少年和糖尿病控制不良的年轻人的血糖控制。

著录项

  • 作者

    Lewis, Kevin R.;

  • 作者单位

    West Virginia University.;

  • 授予单位 West Virginia University.;
  • 学科 Nursing.
  • 学位 D.N.P.
  • 年度 2013
  • 页码 60 p.
  • 总页数 60
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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