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首页> 外文学位 >Clinical investigation of the major and minor salivary glands in patients with autoimmune diseases (Sjogren's syndrome and idiopathic inflammatory myopathies) and in patients wearing complete dentures (Hungarian text).
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Clinical investigation of the major and minor salivary glands in patients with autoimmune diseases (Sjogren's syndrome and idiopathic inflammatory myopathies) and in patients wearing complete dentures (Hungarian text).

机译：自身免疫性疾病患者（干燥综合征和特发性炎症性肌病）和全口假牙患者的唾液腺的主要和次要的临床研究（匈牙利文）。

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Objective of this study was to describe the oral properties of Sjogren's syndrome (SS) and idiopathic inflammatory myopathies (IIM) compared to healthy controls. Particular attention was given to the determination of palatal salivary flow rate and the subjective problems associated with denture wearing in SS patients. A further aim was to compare the unstimulated whole (UWS) and palatal (PS) saliva flow rates of patients wearing complete dentures and patients with SS and to test whether xerostomia or hyposalivation has a negative influence on maxillary complete denture stability. A third aim was to determine the influence of new complete dentures on UWS and PS flow rates in healthy individuals. Subjects And Methods: In the SS and the IIM groups after the determination of their general health state a questionnaire was employed to obtain and record the subject's symptoms. Clinical assessments were made of their oral mucosal, dental and periodontal and denture status. Sialometric tests were performed to determine the flow rates of unstimulated whole (WS) and in the SS-group: palatal saliva (PS). In the IIM-group: light- and electron microscopic analysis of the symptoms of capillary abnormalities or signs of focal infiltration in labial biopsy specimens were carried out; for comparison with healthy controls. The masticatory force (MF) and the handgripping force was measured with a specially developed device. All participants in the third study were questioned about possible subjective oral complaints (xerostomia or instability of the dentures), through use of a standardized questionnaire. UWS and PS flow rates of the healthy subjects (controls) and of the SS-patients were measured. In the fourth part of the study, new complete dentures were fabricated for healthy patients. Flow rates of UWS and PS were measured before ans seven days after the insertion in order to compare data with their pre-fabrication values. According to the results, that dental and periodontal status correlate with the possible autoantibody positivity, authors can state that the oral health status of patients both with SS and IIM might be considerably related to the general autoimmune process, and no more than partly to the hyposalivation. SS patients' chief complaint is glossodynia, their most frequent mucosal alteration is the erythema of the hard palate. As it is indicated by the results of this study, IIM patients have significant gingival oedema, and telangiectasia. Dysphagia either because of xerostomia or macroglossia, or secondary to the oesophageal dysmotility, weakness of the masticatory muscles makes eating difficult in IIM. Obtained data strongly suggest that the reduction in the thickness of the palatal film in SS patients is due to a decrease in the volume of the mixed, whole saliva, not to the viscous palatal saliva. Remaining palatal mucous saliva flow can help to stabilize the maxillary complete denture in patients with hyposalivation. Neither unstimulated whole nor palatal saliva flow rate are influenced by the placement of new dentures in healthy complete denture wearers.
机译：这项研究的目的是描述与健康对照相比，干燥综合征（SS）和特发性炎症性肌病（IIM）的口腔特性。特别要注意SS患者patients唾液流速的确定以及与义齿佩戴有关的主观问题。另一个目的是比较佩戴全口义齿的患者和SS患者的未刺激全口齿（UWS）和lat骨（PS）唾液流速，并测试口干症或唾液分泌不足对上颌全口义齿的稳定性是否有负面影响。第三个目标是确定健康个体中新的全口义齿对UWS和PS流速的影响。受试者和方法：在SS和IIM组的总体健康状况确定之后，使用问卷调查表来获取和记录受试者的症状。对他们的口腔粘膜，牙齿，牙周和义齿状态进行了临床评估。进行了口气压测试，以确定未刺激的整体（WS）和SS组：pa唾液（PS）的流速。在IIM组中：对阴唇活检标本中的毛细血管异常症状或局灶性浸润迹象进行了光镜和电镜观察；与健康对照进行比较。咀嚼力（MF）和握力是使用专门开发的设备进行测量的。通过使用标准化问卷，对第三项研究的所有参与者进行了有关可能的主观口腔主诉（口干症或义齿不稳定性）的询问。测量了健康受试者（对照组）和SS患者的UWS和PS流速。在研究的第四部分中，为健康患者制作了新的全口义齿。为了将数据与其预制值进行比较，在插入后7天之前和之后测量UWS和PS的流速。根据结果​​，牙齿和牙周状态与可能的自身抗体阳性相关，作者可以指出，SS和IIM患者的口腔健康状况可能与总体自身免疫过程有很大关系，而不仅仅是与唾液分泌不足有关。 SS患者的主要主诉是舌痛，他们最常发生的粘膜改变是硬pa的红斑。这项研究的结果表明，IIM患者有明显的牙龈水肿和毛细血管扩张。吞咽困难是由于口干或大舌症，或继发于食道运动障碍，咀嚼肌无力使IIM进食困难。获得的数据强烈表明，SS患者patients膜厚度的减少是由于混合的整个唾液的体积减少，而不是粘性的pa唾液减少。唾液分泌不足的患者，残留的lat黏液唾液流量可以帮助稳定上颌全口义齿。在健康的全口义齿佩戴者中，将新的义齿放置在无刺激的全口或pa唾液流速中都不会受到影响。

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