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Puerarin: From the roots of kudzu to the front lines of stress modulation in farmed fish.

机译：葛根素（Puerarin）：从葛根的根源到养殖鱼类的压力调节前沿。

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摘要

Farmed fish reared in aquaculture systems are exposed to physiological stressors from biological, chemical, and physical sources. The consequences of these stressors affect the productivity of farming outcomes by reducing immune response, growth, and development within fish. An 8-week study was performed to determine the effects of supplementing puerarin-the most biologically active ingredient present in the roots of kudzu (Puerarin lobata)-within farmed fish. Chinook salmon (Oncorhynchus tshawytscha) fingerlings were maintained in 10 liter glass tanks at 16 +/- 20C which were supplied with recirculated and aerated dechlorinated water. Puerarin was given to fish through supplementation to commercial fish feed pellets. The results indicated that administration of puerarin through feed supplementation reduces plasma cortisol, protein levels, along with blood hematocrit while improving spleen somatic indices and respiratory burst response over an 8 week period when compared to fish fed a control diet without affecting growth, and thereby counteracts the negative consequences of stress induced through handling and experienced by fish reared in aquaculture. Being one of the first studies to study the effects of puerarin on fish over an extended period, our results are concurrent with prior research with puerarin on other animal models.
机译：在水产养殖系统中养殖的养殖鱼暴露于来自生物，化学和物理来源的生理压力下。这些压力源的后果通过降低鱼类的免疫反应，生长和发育来影响养殖成果的生产力。进行了为期8周的研究，以确定在养殖鱼中补充葛根素（葛根（Puerarin lobata）根中存在的最具生物活性的成分）的效果。将奇努克鲑鱼（Oncorhynchus tshawytscha）的鱼种维持在16 +/- 20℃的10升玻璃水箱中，并向其中供应再循环和充气的脱氯水。葛根素通过补充商业鱼饲料颗粒而用于鱼类。结果表明，与饲喂对照饮食而不影响生长的鱼相比，通过饲喂葛根素可降低血浆皮质醇，蛋白质水平以及血细胞比容，同时在8周的时间内可改善脾体指数和呼吸爆发反应。水产养殖中养育的鱼类因处理而引起的压力的负面影响。作为长期研究葛根素对鱼类影响的首批研究之一，我们的研究结果与先前葛根素对其他动物模型的研究相吻合。

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  • 作者

    Hossain, Mohammed Rumman.;

  • 作者单位

    Purdue University.;

  • 授予单位 Purdue University.;
  • 学科 Physiology.;Cellular biology.;Biology.
  • 学位 M.S.
  • 年度 2013
  • 页码 83 p.
  • 总页数 83
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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