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Biocompatibility and osteogenic potential of new generation endodontic materials using primary osteoblasts.

机译:使用原代成骨细胞的新一代牙髓材料的生物相容性和成骨潜能。

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摘要

Generex A, Generex B, Capasio and Ceramicrete are being introduced as new generation endodontic materials able to facilitate bone healing. The aim of this study was to evaluate the biocompatibility and osteogenic potential of these materials. Primary osteoblasts were exposed to these materials and mineral trioxide aggregate (MTA). Trypan blue staining was used to evaluate cell viability from 1-6 days. Scanning electron microscopy (SEM) was used to visualize mineralized nodules and Energy Dispersive X-ray Analysis (EDXA) to calculate the relative amounts of phosphorous and calcium. Data were analyzed by Kruskal Wallis and Mann Whitney-U tests. Only Generex A and MTA allowed cell growth and proliferation throughout the experiment. Generex A was the only new generation endodontic material that supported primary osteoblast growth; no material tested facilitated mineralization.
机译:Generex A,Generex B,Capasio和Ceramicrete被引入作为能够促进骨愈合的新一代牙髓材料。这项研究的目的是评估这些材料的生物相容性和成骨潜力。原发性成骨细胞暴露于这些物质和三氧化二矿聚集体(MTA)。台盼蓝染色用于评估1-6天后的细胞活力。扫描电子显微镜(SEM)用于可视化矿化的结核,能量分散X射线分析(EDXA)用于计算磷和钙的相对含量。数据通过Kruskal Wallis和Mann Whitney-U检验进行分析。在整个实验过程中,只有Generex A和MTA允许细胞生长和增殖。 Generex A是唯一支持初级成骨细胞生长的新一代牙髓材料。没有经过测试的材料有助于矿化。

著录项

  • 作者

    Washington, Jelani Tenoa.;

  • 作者单位

    The Texas A&M University System Health Science Center.;

  • 授予单位 The Texas A&M University System Health Science Center.;
  • 学科 Health Sciences Dentistry.;Engineering Materials Science.
  • 学位 M.S.
  • 年度 2010
  • 页码 44 p.
  • 总页数 44
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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