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首页> 外文学位 >Toxicokinetics of PCBs and PAHs in green frogs (Rana clamitans) and leopard frogs (Rana pipiens) at various life stages.
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Toxicokinetics of PCBs and PAHs in green frogs (Rana clamitans) and leopard frogs (Rana pipiens) at various life stages.

机译：多氯联苯和多环芳烃在不同生命阶段的绿蛙（蛙蛙）和豹蛙（琵琶蛙）的毒代动力学。

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摘要

In this thesis, chemical elimination studies were conducted in order to quantify chemical exposure dynamics in leopard frogs (Rana pipiens ) and green frogs (Rana clamitans) at various life stages. Two classes of hydrophobic organic chemicals were studied: polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs).;The focus of the first study (Chapter 2) was to determine whether the process of metamorphosis increased the chemical activity (fugacity) of PCBs within amphibians. Green frog tadpoles were dosed with a PCB mixture and allowed to eliminate the chemicals as they underwent metamorphosis. It was observed that the chemical activity of some of the highly hydrophobic PCBs within amphibian tissues increased by a factor of four. This result indicates that the physical changes that occur during metamorphosis increase the potential hazard of highly hydrophobic contaminants to amphibians.;The goal of the second study (Chapter 3) was to quantify elimination kinetics of polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) in adult leopard frogs (Rana pipiens) and green frogs (Rana clamitans). Results show that adult anurans have very low elimination rates of PCBs, but that they exhibit a small capacity for metabolic biotransformation of PAHs.;In the third study (Chapter 4), PCB elimination rates were used to show that green frogs (Rana clamitans) and leopard frogs ( Rana pipiens) at all life stages (tadpole, metamorph, and adult) are capable of metabolic biotransformation of PCBs. (Abstract shortened by UMI.).
机译：在本文中，进行了化学消除研究，以量化处于不同生命阶段的豹蛙（Rana pipiens）和绿蛙（Rana clamitans）的化学暴露动态。研究了两类疏水性有机化学品：多氯联苯（PCB）和多环芳烃（PAH）。；第一个研究（第二章）的重点是确定变态过程是否增加了PCB的化学活性（烟气度）。两栖动物。给绿蛙t添加多氯联苯混合物，并在它们发生变态时消除它们。据观察，两栖动物组织中某些高度疏水的PCB的化学活性增加了四倍。该结果表明，在变态过程中发生的物理变化增加了高度疏水性污染物对两栖动物的潜在危害。;第二项研究（第3章）的目的是量化多氯联苯（PCBs）和多环芳烃（PAHs）的消除动力学）在成年豹蛙（Rana pipiens）和绿蛙（Rana clamitans）中。结果表明，成年无头乌龙对PCB的清除率非常低，但对PAHs的代谢生物转化能力却很小。;在第三项研究（第4章）中，PCB的清除率被用于表明绿蛙（Rana clamitans）和豹蛙（Rana pipiens）在所有生命阶段（ta，变态和成年）都能够进行PCB的代谢生物转化。 （摘要由UMI缩短。）。

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  • 作者

    Leney, Jocelyn.;

  • 作者单位

    University of Windsor (Canada).;

  • 授予单位 University of Windsor (Canada).;
  • 学科 Environmental science.;Zoology.;Ecology.
  • 学位 M.Sc.
  • 年度 2005
  • 页码 100 p.
  • 总页数 100
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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