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首页> 外文学位 >Does Respiratory Syncytial Virus (RSV) infection in the first two years of life contribute to the development of asthma among children in Manitoba?
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Does Respiratory Syncytial Virus (RSV) infection in the first two years of life contribute to the development of asthma among children in Manitoba?

机译：出生后头两年的呼吸道合胞病毒（RSV）感染是否会导致曼尼托巴省儿童哮喘的发展？

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摘要

The study was conducted with a total of 13980 children of the 1995 birth cohort, who were living in Manitoba by the end of December, 2006.;Higher frequency of RSV-associated LRTI before 2 years was associated with higher risks of asthma diagnosis at 7 and 11 years and also with risks of transient wheeze and early persistent asthma. Higher risk of asthma diagnosis was associated with more severe episode(s) of RSV-associated LRTI within the first 2 years of life. First clinically significant RSV-LRTI between 6 and 12 months was associated with the highest risks of asthma diagnosis at 7 and at 11 years. But first RSV-associated LRTI within the first 6 months of life was associated with the highest risk of asthma/transient wheezing before the age of 3 years and early persistent asthma and transient wheeze. These associations were diminishing with increasing age of the children of the study cohort.
机译：这项研究针对的是1995年出生队列的13980名儿童，这些儿童在2006年12月底之前居住在曼尼托巴省。RSV相关的LRTI发生频率在2岁之前较高，与7岁时哮喘诊断的风险较高相关和11岁，还有短暂性喘息和早期持续哮喘的风险。哮喘诊断的较高风险与生命最初2年内与RSV相关的LRTI发作更为严重有关。在6和12个月之间首次出现临床上显着的RSV-LRTI与7和11岁时哮喘诊断的最高风险相关。但是，在生命的前6个月内首次与RSV相关的LRTI与3岁之前哮喘/短暂性喘息以及早期持续性哮喘和短暂性喘息的最高风险相关。随着研究队列中儿童年龄的增加，这些联系正在减少。

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  • 作者

    Khan, Sazzadul Anwar.;

  • 作者单位

    University of Manitoba (Canada).;

  • 授予单位 University of Manitoba (Canada).;
  • 学科 Health Sciences Epidemiology.;Health Sciences Health Care Management.
  • 学位 Ph.D.
  • 年度 2011
  • 页码 261 p.
  • 总页数 261
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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