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Evaluating quality of life, functional capabilities, and coping strategies of people with chronic pain taking opioids versus no opioids.

机译:评估服用阿片类药物与不服用阿片类药物的慢性疼痛患者的生活质量,功能能力和应对策略。

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摘要

Chronic non-malignant pain (CNP) represents a significant challenge for 80 million Americans who suffer with these intractable pains that are resistant to medical interventions. Many people with CNP must rely on the use of opioids, such as MS ContinRTM, Duragesic PatchRTM, Oramorph SRRTM, and OxyContinRTM for long-term pain relief. Opioid therapy for the treatment of CNP, however, has been hotly debated. Concerns about opioid therapy have stemmed from claims about addiction liability, tolerance to opioid analgesia, cognitive impairment, and alterations in physical functioning. Central to the debate over opioid therapy is the issue of the impact of opioids on the patient's quality of life, including functional capabilities.; A telephone survey of 89 individuals with chronic non-malignant pain attending the University of Wisconsin's Pain or Rehabilitation Clinics revealed 56 (63%) consistently used opioids for pain relief and 33 (37%) did not use opioids. Differences were reported in the physical component summary (PCS) of the SF-36v2 revealing that individuals on opioid therapy had significantly more bodily pain (p = .002), more physical dysfunction ( p = .006), and physical role limitations (e.g., difficulty performing work, limited in the kind of work) (p = .005). However, similar percentage of opioid users (20%, n = 11) and non-opioid users (18%, n = 6) either worked full-time or went to school full-time. No differences were discovered in the mental component summary (MCS) of the SF-36v2 between the two groups. Utilizing the Graded Chronic Pain Scale (GCPS), opioid-users reported more severe, life interfering (Grade 4) chronic pain (p = .008) compared to non-opioid users. The Quality of Life Scale (QOLS) found opioid-users were significantly less satisfied ( p = .009) in various life areas (e.g., health, work, socializing, and active recreation) than individuals not using opioids. Aside from "taking pain medication", there were no significant differences in the behavioral and cognitive coping strategies both groups used for pain relief.
机译:慢性非恶性疼痛(CNP)对于承受这些难以忍受医疗干预的顽固性疼痛的8000万美国人构成了重大挑战。许多患有CNP的人必须依靠使用阿片类药物来缓解长期疼痛,例如MS ContinRTM,Duragesic PatchRTM,Oramorph SRRTM和OxyContinRTM。然而,阿片类药物疗法对CNP的治疗引起了激烈的争论。有关阿片类药物治疗的担忧源于对成瘾性的责任,对阿片类药物镇痛的耐受性,认知障碍和身体机能的改变。关于阿片类药物治疗的辩论的核心是阿片类药物对患者生活质量(包括功能能力)的影响。在威斯康星大学疼痛或康复诊所对89位患有慢性非恶性疼痛的人进行的电话调查显示,持续使用阿片类药物缓解疼痛的有56名(63%),没有使用阿片类药物的33名(37%)。在SF-36v2的物理成分摘要(PCS)中报告了差异,这表明接受阿片类药物治疗的人的身体疼痛(p = .002),身体功能障碍(p = .006)和身体角色限制(例如, ,工作困难,工作种类有限(p = .005)。但是,全职工作或全职上学的阿片类药物使用者(20%,n = 11)和非阿片类药物使用者(18%,n = 6)的百分比相似。两组之间在SF-36v2的心理成分摘要(MCS)中未发现差异。与非阿片类药物使用者相比,阿片类药物使用者通过使用渐变慢性疼痛量表(GCPS),报告了更为严重的生活干扰(第4级)慢性疼痛(p = 0.008)。生活质量量表(QOLS)发现,与未使用阿片类药物的人相比,使用阿片类药物的人在各个生活领域(例如健康,工作,社交和积极娱乐)的满意度明显降低(p = .009)。除了“服用止痛药”外,两组用于缓解疼痛的行为和认知应对策略均无显着差异。

著录项

  • 作者

    Adams, Nancy Jane.;

  • 作者单位

    The University of Wisconsin - Madison.;

  • 授予单位 The University of Wisconsin - Madison.;
  • 学科 Health Sciences Rehabilitation and Therapy.; Psychology General.
  • 学位 Ph.D.
  • 年度 2002
  • 页码 137 p.
  • 总页数 137
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 康复医学;心理学;
  • 关键词

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