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首页> 外文学位 >Differential effects of electroconvulsive therapy (ECT) on verbal and visuo-spatial functions in depressed patients.
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Differential effects of electroconvulsive therapy (ECT) on verbal and visuo-spatial functions in depressed patients.

机译：电痉挛疗法（ECT）对抑郁症患者言语和视觉空间功能的不同作用。

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摘要

Electroconvulsive therapy (ECT) is a safe and effective means of rapidly treating patients with severe depression. However, the side effects of ECT on verbal and visuo-spatial memory are of concern. Previous research presents conflicting evidence about the effects of bilateral (BL) and right unilateral (RUL) ECT on memory function. Some differences may be due to varying practices in the administration of ECT before the mid 1980s.;This study compared the differential effects of BL and RUL ECT on verbal and visuo-spatial memory tasks given to patients before and after they received treatment. Scores on the Hopkins Verbal Learning Test (HVLT), Benton Visual Retention Test (BVRT), Benton Supraspan, Trail Making Test, Neurobehavioral Cognitive Status Exam, Montgomery and Asberg Depression Rating Scale, and the Subjective Memory Questionnaire, were examined to determine how ECT affects various aspects of cognitive function. A review of medical records was also conducted. Repeated measures analysis of variance was used to evaluate the effect of RUL and BL ECT on pretest and posttest scores on the neuropsychological and psychological measures.;RUL and BL ECT patients showed similar responses to neuropsychological and psychological measures over time. Significant main effects for both groups were found on verbal tasks, with scores on the HVLT decreasing. Scores for tests of attention showed significant differences for both groups, with Benton Supraspan scores decreasing, and time to completion of Trails B and D increasing. Depression ratings were significantly lower after ECT, and perceived memory ability was significantly higher for both groups.;The similarity of performance for both groups would seem to indicate that there are no significant differences between the groups as a result of the treatment. However, observed differences between means in this study suggest the possibility of improved performance by the RUL ECT group on at least some cognitive measures, and this possibility should be explored in future research. It was suggested that the effects of RUL and BL ECT might lie in subtle, and less easily measured, aspects of cognition.
机译：电抽搐疗法（ECT）是一种快速有效的治疗重度抑郁症患者的安全有效方法。但是，ECT对言语和视觉空间记忆的副作用值得关注。先前的研究提出了关于双侧（BL）和右单侧（RUL）ECT对记忆功能影响的相互矛盾的证据。某些差异可能是由于1980年代中期之前ECT的管理方式不同所致。本研究比较了BL和RUL ECT对患者接受治疗前后的言语和视觉空间记忆任务的不同作用。检查了霍普金斯语言学习测验（HVLT），本顿视觉保持测验（BVRT），本顿Supraspan，追踪制作测验，神经行为认知状态测验，蒙哥马利和阿斯伯格抑郁量表以及主观记忆问卷的分数，以确定如何进行ECT影响认知功能的各个方面。还对病历进行了审查。重复测量方差分析用于评估RUL和BL ECT对神经心理学和心理测验的测验前和测验分数的影响。随着时间的推移，RUL和BL ECT患者对神经心理学和心理测验的反应相似。两组在口头任务上均具有显着的主要影响，HVLT得分降低。注意测试的分数显示两组均存在显着差异，Benton Supraspan分数下降，而完成B和D步道的时间增加。 ECT后抑郁评分明显降低，两组的感知记忆能力均显着提高。两组的表现相似似乎表明治疗后两组之间无显着差异。但是，在这项研究中观察到的不同手段之间的差异表明，RUL ECT组至少在某些认知措施上可能会改善性能，并且这种可能性应在未来的研究中加以探讨。有人认为，RUL和BL ECT的影响可能在于认知的微妙且难以衡量的方面。

著录项

  • 作者

    Johnson, Mary W.;

  • 作者单位

    University of Pittsburgh.;

  • 授予单位 University of Pittsburgh.;
  • 学科 Psychology Physiological.;Psychology Cognitive.
  • 学位 Ph.D.
  • 年度 2001
  • 页码 71 p.
  • 总页数 71
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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