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Serum IgG antibody responses to periodontal pathogens among pediatric subjects.

机译：儿科受试者中血清IgG抗体对牙周病原体的反应。

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The first part of this thesis details the results from an observational study of 303 children 9-11 years of age. An immuno-checkerboard assay was used to analyze IgG levels for 18 different bacteria. Nearly half of the subjects tested positive for at least one orange complex bacteria and to A .actinomycetemcomitans. A higher proportion of females had positive IgG responses to 14 of the 18 bacteria. A significantly higher proportion of African Americans exhibited IgG responses for P. gingivalis, T. denticola, P. intermedia, P. nigrescens, A. actinomycetemcomitans and C. rectus (P0.05). This cross sectional study indicates that a sizable proportion of young patients may be exposed and elicit an immune response to known periodontal pathogens. Recent evidence suggests that obesity and nutrition may be associated with periodontal disease. These two modifiable risk factors and their effects on periodontal disease are discussed in detail in the second part of this thesis.

机译：本文的第一部分详细介绍了对303名9-11岁儿童的观察性研究结果。免疫棋盘法用于分析18种不同细菌的IgG水平。近一半的受试者对至少一种橙色复杂细菌和放线杆菌进行了测试。较高比例的雌性对18种细菌中的14种有阳性IgG反应。显着更高比例的非裔美国人表现出对牙龈卟啉单胞菌，齿状锥虫，中间媒介杆状菌，黑线霉菌，放线杆菌和直肌弯曲菌的IgG反应（P <0.05）。这项横断面研究表明，相当多的年轻患者可能会暴露并引起对已知牙周病原体的免疫反应。最近的证据表明，肥胖和营养可能与牙周疾病有关。本文的第二部分详细讨论了这两个可改变的危险因素及其对牙周疾病的影响。

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作者
Allen, Ronan.;
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作者单位

The University of North Carolina at Chapel Hill.;

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授予单位 The University of North Carolina at Chapel Hill.;
学科 Health Sciences Dentistry.
学位 M.S.
年度 2009
页码 86 p.
总页数 86
原文格式 PDF
正文语种 eng
中图分类口腔科学;
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1. Serum IgG antibody response to periodontal pathogens in minority populations: relationship to periodontal disease status and progression. [J] . Craig RG, Boylan R, Yip J, Journal of periodontal research . 2002,第2期

机译：少数人群对牙周病原体的血清IgG抗体反应：与牙周疾病状态和进展的关系。
2. Serum IgG Antibody Response to Antigens of Presumed Periodontal Pathogens: A Case-control Study using ELISA and Western Blot Analysis [J] . M. A. Curtis, J. M. Slaney, R. J. Carman, Microbial Ecology in Health and Disease . 1990,第5期

机译：血清IgG抗体对牙周病原体抗原的应答：使用ELISA和Western Blot分析的病例对照研究
3. Serum IgG Antibodies Reactive with Potential Periodontal Pathogens and Other Subgingival Plaque Bacteria in a Population of Male British Adolescents with Minimal Destructive Periodontitis [J] . J. M. A. Wilton, J. M. Slaney, J. A. C. Sterne, Microbial Ecology in Health and Disease . 1991,第6期

机译：血清IgG抗体与潜在的牙周病原体和其他牙龈下菌斑细菌反应的男性破坏力最小的男性英国青少年人群中
4. Anti-citrullinated protein antibodies show IgG-type specific changes compared to matched controls in human serum, plasma, and synovial fluid [C] . Susanna L Lundstrom, Catia Cerqueira, Elena Ossipova, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：与人血清，等离子体和滑膜液中的匹配对照相比，抗瓜氨酸蛋白抗体显示IgG型比变化
5. Disease risk factors and humoral antibody response to periodontal-associated pathogens: A model to evaluate periodontal disease in older adults [D] . Schneider, Sandra Lee 1990

机译：疾病危险因素和对牙周相关病原体的体液抗体反应：评估老年人牙周疾病的模型
6. Prognosis of periodontitis recurrence after intensive periodontal treatment using examination of serum IgG antibody titer against periodontal bacteria [O] . Noriko Sugi, Koji Naruishi, Chieko Kudo, 2011

机译：使用针对牙周细菌的血清IgG抗体滴度检查强化牙周治疗后牙周炎复发的预后
7. Serum IgG Antibodies Reactive with Potential Periodontal Pathogens and Other Subgingival Plaque Bacteria in a Population of Male British Adolescents with Minimal Destructive Periodontitis [O] . J. M. A. Wilton, J. M. Slaney, J A. C. Sterne, 1991

机译：血清IgG抗体与潜在的牙周病原体和其他龈下菌斑细菌在具有最小破坏性牙周炎的男性英国青少年群体中反应

Serum IgG antibody responses to periodontal pathogens among pediatric subjects.

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