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The effects of alternative joint models in the study of lower-limb joint moments in knee osteoarthritis.

机译：替代关节模型在膝骨关节炎下肢关节力矩研究中的作用。

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摘要

Knee osteoarthritis is a disease that affects nearly 40% of the global population over the age of seventy. It is believed that the incidence and progression of osteoarthritis can be partially attributed to changes in mechanical joint loading. Consequently, changes in lower-limb joint moments are important outcome measures for its treatment and prevention. The purpose of this study was to investigate the effect of four different anatomic joint models on the detection of changes in lower-limb joint moments due to knee osteoarthritis.;Hip adduction magnitude, knee adduction magnitude, peak early-stance knee internal rotation, and peak ankle plantarflexion moments were different between groups regardless of joint model. Differences detected using principal component analysis were less sensitive to the choice of joint model. Results support adoption of the Joint Coordinate System as a standard for joint moment expression due to its clinical relevance and ability to detect differences due to moderate knee osteoarthritis.;Moments during gait were calculated for 44 subjects with moderate osteoarthritis and 44 asymptomatic subjects, then expressed using four joint models: Joint Coordinate System, Plane of Progression, Distal, and Proximal. Discrete peak measures and principal component scores were compared between groups.
机译：膝盖骨关节炎是一种疾病，影响了70岁以上的全球人口中近40％。相信骨关节炎的发生和发展可以部分归因于机械关节负荷的变化。因此，下肢关节力矩的变化是其治疗和预防的重要结果指标。这项研究的目的是研究四种不同的解剖学关节模型在检测由于膝骨关节炎引起的下肢关节力矩变化中的作用。髋内收幅度，膝内收幅度，早期站立膝关节内部旋转峰值和两组的踝关节plant屈峰值峰值均不同，与关节模型无关。使用主成分分析检测到的差异对关节模型的选择不太敏感。由于其临床意义和能够检测出中度膝骨关节炎引起的差异的能力，结果支持采用关节坐标系统作为关节力矩表达的标准。;计算了44例中度骨关节炎和44例无症状受试者的步态力矩。使用四个关节模型：关节坐标系，渐进平面，远端和近端。比较两组之间的离散峰值量度和主成分评分。

著录项

  • 作者

    Brandon, Scott C. E.;

  • 作者单位

    Queen's University (Canada).;

  • 授予单位 Queen's University (Canada).;
  • 学科 Engineering Mechanical.
  • 学位 M.Sc.Eng.
  • 年度 2009
  • 页码 83 p.
  • 总页数 83
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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