首页> 外文学位 >Analyses of pericentromeric regions of soybean (Glycine max L. Merr.) and comparative genomics study of euchromatic regions between soybean and common bean (Phaseolus vulgaris).
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Analyses of pericentromeric regions of soybean (Glycine max L. Merr.) and comparative genomics study of euchromatic regions between soybean and common bean (Phaseolus vulgaris).

机译:大豆(Glycine max L. Merr。)的着丝粒区域分析和大豆与普通豆(菜豆)之间的常染色体区域的比较基因组学研究。

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摘要

Soybean (Glycine max) has undergone several rounds of polyploidization and subsequent diploidization. Thus, the present day genome is a paleopolyploid mosaic of homeologous regions derived from whole genome duplications. To reveal the impact of these evolution events on the structure and function of homeologous regions, structural and functional analyses were done for two ∼1mb euchromatic homeologous regions of soybean and an orthologous region from common bean (Phaseolus vulgaris). One of the soybean homoelogous regions (Gm15) underwent more severe structural changes (one inversion ∼0.6 mb and two deletions ∼50 kb and ∼150 kb), more extensive gene movement, and biased accumulation and deletion of LTR retrotransposons. Functional analyses of the two soybean homeologous regions revealed decreases in gene expression and biases in synonymous substitution rates for the same homeologous region. Subfunctionalization of homeologs after duplication was also analyzed by looking at divergent expression patterns among different tissues and developmental stages. Our results indicate asymmetric evolution between homeologous regions after duplication via structural changes and functional changes in gene activity.
机译:大豆( Glycine max )已经经历了几轮多倍体化和随后的二倍体化。因此,今天的基因组是源自全基因组重复的同源区域的古多倍体镶嵌体。为了揭示这些进化事件对同源区域的结构和功能的影响,对大豆的两个〜1mb的常染色体同源区域和普通豆的直系同源区域( Phaseolus vulgaris )进行了结构和功能分析。 。大豆同源区域之一(Gm15)发生了更严重的结构变化(一个倒置〜0.6 mb和两个删除〜50 kb和〜150 kb),更广泛的基因运动以及LTR逆转座子的积累和缺失偏向。对两个大豆同源区域的功能分析表明,基因表达下降,同一个同源区域的同义替代率存在偏差。通过观察不同组织和发育阶段之间的差异表达模式,也分析了复制后同源物的亚功能。我们的结果表明复制后同源结构之间的不对称进化通过基因活性的结构变化和功能变化。

著录项

  • 作者

    Lin, Jer-Young.;

  • 作者单位

    Purdue University.;

  • 授予单位 Purdue University.;
  • 学科 Agriculture Agronomy.;Agriculture Plant Culture.
  • 学位 Ph.D.
  • 年度 2009
  • 页码 185 p.
  • 总页数 185
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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