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首页> 外文学位 >Characterization of Staphylococcus aureus isolates associated with pediatric carriage in Houston, Texas.
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Characterization of Staphylococcus aureus isolates associated with pediatric carriage in Houston, Texas.

机译：金黄色葡萄球菌分离物的特征与小儿马车在德克萨斯州休斯敦市有关。

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摘要

Infections caused by Methicillin-resistant Staphylococcus aureus (MRSA) have been of great concern in hospitals due the difficulty in treating virulent, antibiotic resistant microorganisms in sensitive populations including children, the elderly, and immunocomprimised individuals. Since the late 1990's, MRSA infections have become a problem in the general community, and the strains of S. aureus that cause infections in the community are known to be genetically different than the hospital acquired strains. Community-acquired strains tend to be more virulent, affecting even relatively healthy individuals, and disease presentation tends to be more diverse than diseases observed in patients suffering from hospital-acquired strains. From the year 2000 to the present, there has been a significant increase in community-acquired infections in children, a population already particularly sensitive to S. aureus infection. Genotyping the strains of CA-MRSA circulating in the pediatric population is an important step in developing better antibiotic treatment strategies. Additionally, determining the carriage status of individuals in this population and comparing these data with strain genotypes will also be valuable in establishing prevention and control practices.
机译：耐甲氧西林金黄色葡萄球菌（MRSA）引起的感染已在医院引起了广泛关注，因为在包括儿童，老年人和免疫功能低下的人群中，难以治疗有毒力的，具有抗生素抗性的微生物。自1990年代后期以来，MRSA感染已成为整个社区的问题，众所周知，引起社区感染的金黄色葡萄球菌菌株与医院获得的菌株在遗传上有所不同。社区获得性毒株往往更具毒性，甚至会影响相对健康的个体，而且与在医院获得性毒株的患者身上观察到的疾病相比，疾病表现形式往往更加多样化。从2000年至今，社区获得性感染儿童的数量已大大增加，儿童已经对金黄色葡萄球菌感染特别敏感。对在儿科人群中传播的CA-MRSA菌株进行基因分型是制定更好的抗生素治疗策略的重要步骤。此外，确定该人群中个体的携带状况并将这些数据与菌株基因型进行比较，对于建立预防和控制措施也将非常有价值。

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  • 作者

    Dunkle, Jesse W.;

  • 作者单位

    The University of Texas School of Public Health.;

  • 授予单位 The University of Texas School of Public Health.;
  • 学科 Biology Microbiology.;Health Sciences Epidemiology.
  • 学位 M.P.H.
  • 年度 2009
  • 页码 41 p.
  • 总页数 41
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 微生物学;
  • 关键词

  • 入库时间 2022-08-17 11:38:28

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