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Heterogeneities in the 20S proteasome complexes: Molecular organization, assembly and function.

机译：20S蛋白酶体复合物中的异质性：分子的组织，组装和功能。

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The cardiac proteasome is increasingly recognized as a complex, heterogeneous and dynamic organelle contributing to the modulation of cardiac function in health and diseases. The emerging picture of the proteasome system reveals a highly regulated and organized molecular machine integrated into multiple biological processes of the cell. Full appreciation of its cardiovascular relevance requires an understanding of its proteolytic function as well as its underlying regulatory mechanisms; of which assembly, stoichiometry, post-translational modification and the role of the associating partners are increasingly poignant.

机译：心脏蛋白酶体日益被认为是复杂，异质和动态的细胞器，有助于调节健康和疾病中的心脏功能。蛋白酶体系统的新兴图片揭示了高度调控和组织良好的分子机器，该机器整合到细胞的多个生物过程中。充分了解其心血管相关性需要了解其蛋白水解功能及其潜在的调控机制。其中装配，化学计量，翻译后修饰以及相关伙伴的作用越来越令人发指。

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作者
Young, Glen William.;
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作者单位

University of California, Los Angeles.;

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授予单位 University of California, Los Angeles.;
学科 Biology Cell.;Chemistry Biochemistry.
学位 Ph.D.
年度 2009
页码 151 p.
总页数 151
原文格式 PDF
正文语种 eng
中图分类
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入库时间 2022-08-17 11:38:30

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1. The two PAN ATPases from Halobacterium display N-terminal heterogeneity and form labile complexes with the 20S proteasome [J] . Bruno Franzetti, Dorian Guetta, Hala Chamieh The biochemical journal . 2008,第2期

机译：嗜盐杆菌中的两个PAN ATPase显示N末端异质性并与20S蛋白酶体形成不稳定的复合物
2. The two PAN ATPases from Halobacterium display N-terminal heterogeneity and form labile complexes with the 20S proteasome [J] . Chamieh H, Guetta D, Franzetti B The Biochemical Journal . 2008,第2期

机译：嗜盐杆菌中的两个PAN ATPase显示N末端异质性并与20S蛋白酶体形成不稳定的复合物
3. Molecular Organization of the 20S Proteasome Gene Family from Arabidopsis thaliana [J] . Cassandra S. Arendt, Hongyong Fu, Jed H. Doelling, Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 1998,第2期

机译：拟南芥20S蛋白酶体基因家族的分子组织
4. Development of molecular agents for 20S proteasome targeting [C] . Pascal Furet, Patricia Imbach, Vito Guagnano International Peptide Symposium;European Peptide Symposium . 2005

机译：20S蛋白酶体靶向的分子试剂的发展
5. Design and synthesis of core structural intermediates for novel HIV-1 protease inhibitors and synthesis, biological activity and molecular modeling of novel 20S proteasome inhibitors. [D] . Avancha, Kiran Kumar Venkata Raja. 2006

机译：新型HIV-1蛋白酶抑制剂的核心结构中间体的设计与合成，新型20S蛋白酶体抑制剂的合成，生物学活性和分子建模。
6. Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. [O] . H Fu, J H Doelling, C S Arendt, 1998

机译：拟南芥20S蛋白酶体基因家族的分子组织。
7. The 2 PAN ATPases from Halobacterium display N-ter heterogeneity and form labile complexes with the 20S proteasome. [O] . Chamieh, Hala, Guetta, Dorian, Franzetti, Bruno 2008

机译：嗜盐杆菌的2个PAN ATP酶显示N-ter异质性，并与20S蛋白酶体形成不稳定的复合物。

Heterogeneities in the 20S proteasome complexes: Molecular organization, assembly and function.

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