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Developing Safe and Controllable Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Therapies with Design Principles of Synthetic Biology

机译：制定安全可控的集群定期间隙的短语重复（CRISPR），基于合成生物学的设计原则 - 基于设计原则的疗法

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作者
Moghadam, Farzaneh.;
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作者单位

Arizona State University.;

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授予单位 Arizona State University.;
学科
学位 Ph.D.
年度 2020
页码 217 p.
总页数 217
原文格式 PDF
正文语种 eng
中图分类 AAI28030865;
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1. Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/CRISPR-Associated Endonuclease Cas9-Mediated Homology-Independent Integration for Generating Quality Control Materials for Clinical Molecular Genetic Testing [J] . Lin Guigao, Zhang Kuo, Peng Rongxue, The Journal of molecular diagnostics: JMD . 2018,第3期

机译：聚集定期间隙短的回文重复（CRISPR）/ CRISPR相关的内切核酸CAS9介导的同源无关集成，用于产生临床分子遗传检测的质量控制材料
2. Subtyping Salmonella enterica Serovar Enteritidis Isolates from Different Sources by Using Sequence Typing Based on Virulence Genes and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) [J] . Fenyun Liu, Subhashinie Kariyawasam, Bhushan M. Jayarao, Applied and Environmental Microbiology . 2011,第13期

机译：通过使用基于毒力基因和成簇的规则间隔短回文重复序列的序列分型，对来自不同来源的肠炎沙门氏菌肠炎沙门氏菌进行亚型分型
3. Subtyping Salmonella enterica Serovar Enteritidis Isolates from Different Sources by Using Sequence Typing Based on Virulence Genes and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) [J] . Fenyun Liu, Subhashinie Kariyawasam, Bhushan M. Jayarao, Applied and Environmental Microbiology . 2011,第13期

机译：通过使用基于毒力基因和成簇的规则间隔短回文重复序列的序列分型，对来自不同来源的肠炎沙门氏菌肠炎沙门氏菌进行亚型分型
4. Incorporation of inherently safer design principles in process safety assurance: Association with risk assessment and use of risk-based approach [C] . Ming Yang Institution of Chemical Engineers Symposium on Hazards . 2018

机译：加工安全保障中固有的更安全设计原则：与风险评估和基于风险的方法的关联
5. Clustered regularly interspaced short palindromic repeat (CRISPR)-mediated development of an improved model for metastatic renal cell carcinoma [D] . Schokrpur, Shiruyeh 2015

机译：聚类的规则间隔的短回文重复（CRISPR）介导的转移性肾细胞癌改良模型的开发
6. Effects of clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) protein 9 system-Based Deletion of miR-451 in Mouse Embryonic Stem Cells on Their Self-Renewal and Hematopoietic Differentiation [O] . Su-Jin Kim, Chang-Hoon Kim, Borim An, 2017

机译：基于簇的规则间隔的短回文重复（CRISPR）/ CRISPR相关（Cas）蛋白9系统在小鼠胚胎干细胞中对miR-451的删除对其自我更新和造血分化的影响
7. Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/CRISPR-Associated Endonuclease Cas9–Mediated Homology-Independent Integration for Generating Quality Control Materials for Clinical Molecular Genetic Testing [O] . Guigao Lin, Kuo Zhang, Rongxue Peng, 2018

机译：聚集定期间隙短的回文重复（CRISPR）/ CRISPR相关的内切核酸酶CAS9介导的同源性无关集成，用于产生临床分子遗传检测的质量控制材料

Developing Safe and Controllable Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Based Therapies with Design Principles of Synthetic Biology

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