In this paper we measured salivary β2 microglobulin (β2,m) concentration in 4o patients with Sjogren’S syndrome, including 20 patients with systemic lupus erythematosus, 12 patients with recurrent aphthous ulceration and 16 patients with single xerostomia, and in 40 normal controls. The results showed that salivary β2m concentration was more significantly elevated in Sjogren’s syndrome patients, compared with that in both normals and other patients. The measurement of β2m concentration in saliva may offer a simple and valuable method for diagnosis of Sjogren’s syndrome.
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