Objective;To investigate the etiology, clinical features, imaging characteristics, management and prognosis of hemorrhagic transformation (HT) in acute ischemic stroke patients. Methods Retrospective a-nalysis was performed in 656 acute ischemic stroke patients admitted in our hospital between Sep. 2008 and Feb. 2011. Of the total patients,32 ( male, 18; female, 14 ) occurred hemorrhagic transformation and were reviewed regarding the etiology of HT, clinical performance,MR and CT imaging findings as well as comprehensive treatment. Results: Risk factors of HT included extensive cerebral infarction, particularly cerebral embolism caused by atrial fibrillation. Most cases had a good outcome, though, those complicated with broad spectrum of parenchymal cerebral hematoma remained poor prognosis, after therapeutic protocols being properly adjusted. Conclusion-. Suspected patients should undergo repeat routine CT/ MRI examination and timely adjustment of the therapy plan, since HT is associated with early signs of large area cerebral infarction and embolism.%目的:探讨急性脑梗死出血性转化的病因、临床特点、影像学表现、治疗及预后.方法:回顾分析自2008年9月～2011年2月收治的急性脑梗死患者共656例,其中有出血性转化的共32例(男18例,女14例),从病因、临床特点、MR和CT影像学征象及综合性治疗等进行回顾性总结.结果:32例出血性转化患者中大面积脑梗死占多数,尤其是房颤引起的脑栓塞.经调整治疗,多数预后良好,只有脑实质内血肿面积较大患者预后较差.结论:大面积脑梗死及脑栓塞患者易继发出血性转化,对可疑患者应常规复查头颅CT/MRI及时调整治疗方案.
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