Objective To investigate the maternal complications and pregnancy outcomes of twin pregnancy conceived with assisted reproductive techniques(ART),and provide evidence for prenatal monitoring and obstetric management of twin preg-nancy with ART.Methods Clinical data were analyzed retrospectively of maternal general conditions,pregnancy complications, mode of delivery and perinatal outcomes of 165 twin pregnancies conceived by ART(ART group)and 220 spontaneous twin pregnancies(natural pregnancy group).Results The women in ART group were (31.8±3.40)years old in average,their age significantly higher than that in natural pregnancy group.There was significant difference between two groups(P<0.01).The proportion of women over 35 years old and primipara in ART group was significantly higher than in natural pregnancy group(P<0.01).The completing rate of prenatal examination in ART group was significantly higher than in natural pregnancy group (P<0.01).The rate of cesarean section in ART group was significantly higher than in natural pregnancy group(P<0.05) .The incidence of mild preeclampsia,placenta previa and postpartum hemorrhage in ART group was significantly higher than in natural pregnancy group(P<0.05).The average weight of newborns in ART group was significantly greater than in natural pregnancy group(P<0.05).The incidence of stillbirth in ART group was significantly lower than in natural pregnancy group (P<0.05).Conclusion As women who have twin pregnancy conceived with ART are usually elderly parturient women and primipara,they are more at risk of developing pregnancy complications.However,it was found in this study that adverse perina-tal outcomes don’t increase if more attention is paid to prenatal care and cesarean section is preferred in these women.%目的：探讨辅助生育技术(ART)助孕双胎妊娠并发症及结局，为 ART助孕双胎产前监护与产科管理提供依据。方法回顾性分析165例经 ART助孕的双胎妊娠妇女(ART助孕组)和220例自然受孕双胎妊娠妇女(自然受孕组)，比较两组孕妇的一般情况、分娩方式、妊娠期并发症和围产儿结局。结果 ART 助孕组孕妇平均年龄(31.8±3.40)岁，显著大于自然受孕组(28.71±4.09)岁，差异有统计学意义(P<0.01)；ART助孕组的高龄孕妇(年龄≥35岁)及初产妇比例均显著高于自然受孕妇女(均P<0.01)；按计划产前检查完成率显著高于自然受孕组(P<0.01)；孕妇的剖宫产率高于自然受孕组(P<0.05)；孕妇轻度子痫前期、前置胎盘及产后出血的发生率高于自然受孕组，差异有统计学意义(均P<0.05)；ART助孕组新生儿平均体重高于自然受孕组，死胎发生率低于自然受孕组，差异有统计学意义(均P<0.05)。结论辅助生育技术双胎妊娠高龄产妇、初产妇所占比例较高，患妊娠期并发症的风险增加，由于更注重孕期保健，更多选择剖宫产终止妊娠，因此没有观察到围生儿不良结局增多。
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