目的 探讨出口梗阻型便秘(OOC)3种类型不同治疗方案的疗效及其关联性因素.方法 将115例OOC患者作为研究对象,针对不同类型的OOC采用不同的治疗方案,回顾性分析所有患者的临床资料,将可能影响疗效的因素引入回归分析,通过Spearman相关性分析,得出影响疗效的关联性因素.结果 ① 治愈11例,好转59例,未愈45例;好转率为60.87%;② 年龄越大的患者治疗效果越不明显,而治疗时间越长的患者疗效更为显著;③ 盆底松弛型疗效与快速收缩、持续性收缩和测试后基线呈负相关性(P=0.011、0.003、0.000);④ 痉挛型和混合表现型疗效仅与年龄呈正相关性(P=0.000、0.009).结论 用生物反馈对不同类型OOC进行不同针对性方案治疗,疗效确切;年龄和Glazer评估参数与疗效相关联,对不同类型OOC患者治疗方案的选择有指导意义.%Objective To investigate the curative effect of the three types of treatment of outlet obstructive constipation(OOC) and related factors.Methods 115 cases of OOC patients were enrolled in this study, for different types of OOC using different treatment programs, retrospective analysis was used to observe the clinical data of all patients.Spearman correlation analysis was used to find the factors that may affect the clinical effects.Results ① 11 patients were cured;the symptom of 59 patients were alleviated;45 patients were not healed;the average improvement rate was 60.87%.② The older the treatment effect was less obvious, and the longer the treatment time the effect was more significant.③ The effect of RPFS constipation, fast twitch and the sustained twitch correlated with the after test baseline negatively(P=0.011,0.003,0.000).④ Curative effect of spastic type and mixed phenotype only correlated with age positively(P=0.000,0.009).Conclusion Through biological feedback, treating the different types of OOC with individualized treatment plan could contribute to a curative effect.Age is correlated with Glazer evaluation and the curable effect.The findings provides clinical directive significance of the selection of treatment schedules for the different types of OOC.
展开▼
