Myocardial ischemia reperfusion injury is closely related to a number of apoptosis related genes. Fas/FasL system plays a key role in myocardial ischemia reperfusion injury. It is one way of causing apoptosis and one of the critical mediators of cardiac myocyte apoptosis signal transduction. This article reviews current research in the Fas/FasL system and myocardial ischemia reperfusion apoptosis.%心肌缺血再灌注损伤与众多凋亡基因密切相关.Fas/FasL系统在心肌缺血再灌注损伤中起关键作用,是引起细胞凋亡的主要途径之一,是直接启动细胞凋亡信号传导的系统之一.Fas/FasL系统与心肌缺血再灌注细胞凋亡及其信号传导机制是目前国内外研究的热点,现对该问题做一综述.
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