Coronary artery ectasia (CAE) is a common clinical coronary artery disease. Coronary angiography is the main diagnostic tool for CAE, however, at present the pathogenesis of the disease remains unclear. Some research has indicated that excessive stimulation to vascular endothelial of nitric oxide or inflammation hypothesis may involved in pathogenesis. CAE is often associated with coronary heart disease , so primary prevention of coronary heart disease and secondary prevention measures also apply to patients with CAE.%冠状动脉扩张是临床较为常见的冠状动脉疾病,冠状动脉造影是主要的诊断手段,目前该病的发病机制仍不清楚,有学者提出一氧化氮对血管内皮的过度刺激、炎症假说等可能参与发病.该病常合并冠状动脉粥样硬化性心脏病,因此冠状动脉粥样硬化性心脏病的一级和二级预防措施同样适用于冠状动脉扩张患者,硝酸酯类药物能导致患者病变血管的进一步扩张,加重心肌缺血,因此不推荐应用.
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