Objective To Explore the mechanism of the acupuncture on postmenopausal osteoporosis. Method One hundred Wistar female rats(6 month-old)were randomly divided into two groups:Ovariectomized group and sham - operated group. After 3 months of operation, three rats were chosen tomeasure the bone histomorphometric indexes. Then the ovariectomized rats were distributed randomly toacupuncture group and yigaining group and normal saline group and control 2 group,the rots were respec-tively treated by acupuncture and yigaining and normal saline. After the treatment for three course, all ratswere collected blood from the ateria femoralis, the levels of calcitonin were measured by IRMA. The bonehistomorphometric indexes and C - cell in thyroid follicle were detected. Results The levels of calcitoninof acupuncture group were increasing significantly comparing with the yigaining group and the normalsaline group and the control 2 group (p ＜ 0.05),but there were no evident difference in the levels of cal-citonin between the acupuncture group and the sham - operated group. The mean trabecular bone widthand the trabecular bone volume % of acupuncture group were increasing more than that of the normalsaline group and the control 2 group(p ＜ 0.05) ;the mean marrow cavity width and the marrow cavity volume % were derreasing more than that of the nomal saline group and the control 2 group(P ＜ 0.05) ;thenumber of C - cell in thyroid follicle of the acupuncture group were increasing more than that of the othergroups except the sham - operated group. Conclusion Acupuncture can effectively treat the post-menopausal osteoporosis by strengthening the ability of the C - cell in thyroid follicle which can improvethe levels of calcitonin in serum.
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