使用吡啶骨架作为一种容易移除的导向基,发展了铑催化的酚类衍生物与缺电子的烯烃的C-H烯化反应,以较好的收率获得了一系列邻位官能化的酚类化合物.探讨了反应的温度,添加剂,溶剂三种参数对反应收率的影响,建立了最佳的反应条件,并研究了放大量实验.所有未知化合物均采用了IR,NMR,HMMS等谱学技术进行了结构表征.%A highly efficient Rh(Ⅲ)-catalyzed direct C-H olefination of phenol derivatives and withdrawing-electron olefins using readily removable directing group had been developed. A series of functional phenol derivatives were obtained in good yields. The optimal reaction conditions were established through investigation of temperature,additives and solvents,and the gram-scale experi-ment was carried out. Moreover,all of the unknown compounds were confirmed by infrared (IR),nuclear magnetion resonance (NMR),and high resolution mass spectra.
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