Objective To study the clinical value of liver function and serum lipid level in the diagnosis of fatty liver. Methods 54 patients with fatty liver were selected in our hospital from June to December 2013, these patients as the observation group, 54 cases of healthy persons were selected at the same period as the observation group and as control group, two groups of liver function and serum markers were compared and analyzed. Results In the observation group, HDL-C was (1.22±0.84) mmol/L, LDL-C was (3.27±0.23) mmol/L, in the control group, HDL-C was (1.23±0.85) mmol/L,LDL-C was (3.14±0.35)mmol/L, two groups of HDL-C, LDL-C was no significant difference( P>0.05);observation group of TG, TC, ALT, AST levels was higher than the control group,the results between the two groups with significant difference( P<0.05). Conclusion The incidence of fatty liver is driven by liver function and blood lipid abnormality. The examination of liver function and blood gas indexes can provide reference for diagnosis and provide the basis for the analysis of the condition and the prognosis of the patients.%目的：研究分析肝功能和血脂血清指标水平在脂肪肝临床诊断的参考价值。方法根据2013年6～12月我院的54例脂肪肝患者进行研究分析，将这些患者作为观察组，同期选取54例健康体检者作为对照组，对两组肝功能和血清指标进行比较分析。结果观察组 HDL-C为（1.22±0.84）mmol/L、LDL-C 为（3.27±0.23）mmol/L，对照组为（1.23±0.85）mmol/L、（3.14±0.35）mmol/L，两组的 HDL-C、LDL-C 无统计学差异（P ＞0.05）；观察组患者的 TG、TC、ALT、AST 水平比对照组高，两组结果具有统计学差异（P ＜0.05）。结论脂肪肝的发病受到肝功能和血脂异常的推动，对患者进行肝功能和血气指标检查可以为诊断提供参考，对病情分析和预后评估提供依据。
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