The stand or fal performance of SCR denitration catalyst is directly related to the operating effect of denitration system. Through the cause’s analysis of catalyst deactivation due to fouling, wear and poisoning, the paper puts forward the optimization measures in the design and operation.%随着我国对环保要求以及对氮氧化物排放指标要求的不断趋严，选择性催化还原（SCR）脱硝技术在我国得到了广泛的应用，选择性催化还原（SCR）脱硝催化剂性能的好坏直接关系到脱硝系统的运行效果。通过对实际生产中因积灰堵塞、磨损和中毒使催化剂失活的原因分析，提出了在设计和运行等方面的优化措施。
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