目的:研究复方玄驹胶囊联合育之缘口嚼片治疗特发性少弱精子症的临床疗效.方法:以2014年9月至2016年12月期间90例少弱精子症患者作为研究对象,将其随机分配至A组、B组和C组接受不同的治疗,每组各30例.其中A组采用复方玄驹胶囊联合育之缘口嚼片进行治疗,B组采用复方玄驹胶囊口服治疗,C组采用育之缘口嚼片口服治疗.于治疗前和结束后分别检测患者精液参数、外周血清性激素和精液生化指标.结果:1.与治疗前相比,A组和C组患者精子浓度显著提高(P<0.05);A组和B组患者精子活力(a级精子和a+b级精子百分率)和精子活率显著提高(P<0.05);2.与治疗前相比,A组和B组患者外周血清性激素指标水平(FSH、LH 和T)均显著提高(P<0.05);3.与治疗前相比,A组和B组患者精浆果糖指标水平均显著提高(P<0.05),A组和C组患者精浆锌指标水平均显著提高(P<0.05),A组和B组患者精浆中性α-葡萄糖苷酶指标水平均显著提高(P<0.05).结论:复方玄驹胶囊联合育之缘口嚼片治疗特发性少弱精子症患者,可以促进外周血性激素分泌,提高精子活力与密度,改善精液质量.%Objective:To study the effect of Chinese medicine Xuanju compound capsule combined with Yuzhiyuanchewing tablet for the treatment of oligoasthenospermia.Methods: From September 2014 to December 2016,90 cases of patients with oligoasthenospermia were randomly assigned to group-A,group-B and group-C,each group had 30 cases.The A group used Chinese medicine Xuanju compound capsule combined with Yuzhiyuanchewing tablet for treatment,group B served the patients with Chinese medicine Xuanju compound capsule,and group C served patients with Yuzhiyuan chewing tablet oral.Before and after the treatment,the semen parameters,peripheral serum sex hormones and semen biochemical indexes were detected.Results: 1.Compared with before treatment,A group and C group were significantly increased sperm concentration (P<0.05);A group and B group (grade-a and grade a+b) and sperm motility rate increased significantly (P<0.05);2.Patients of A group and B group were significantly increased in the sex hormone level index of peripheral serum (FSH,LH and T) (P<0.05);3 Compared with before treatment,the patients of A group and B group was significantly increased with seminal fructose level index(P<0.05),the patients of A group and C group were significantly increased with seminal plasma zinc levels(P<0.05),the patients of A group and B patients were significantly increased in the seminal plasma of alpha glucosidase level(P<0.05).Conclusion:The treatment of Chinese medicine Xuanju compound capsule combined with Yuzhiyuanchewing tabletfor the oligoasthenospermia patients can promote the peripheral blood sex hormone secretion,improve sperm motility and density,improve semen quality.
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