首页> 中文期刊> 《中国保健营养》 >对比分析常规三联与四联疗法应用于幽门螺杆菌消化道溃疡中的临床疗效

对比分析常规三联与四联疗法应用于幽门螺杆菌消化道溃疡中的临床疗效

         

摘要

Objective To investigate the effect of the treatment of patients with peptic ulcer caused by Helicobacter pylori(Hp)infection with conventional triple therapy and quadruple therapy.Methods to analysis the data selected in 2015 during the-2017 years in the hospital for treatment and diagnosis of patients with Hp positive peptic ulcer clinical data from 200 cases selected according to the received treatment for the 100 patients in each group were divided into A group(conventional triple therapy)and group B(quadruple therapy).By analyzing the clinical data of the patients,the efficacy and safety of conventional triple and quadruple regimen for patients with Hp positive peptic ulcer were summarized.Results the patients of group A eradication rate and ulcer healing rate and patients in group B were different in Hp,B group has more advantages,between groups of data using statistical software processing,P<0.05;two groups of patients in the process of follow-up there were no serious adverse events,the course of treatment after recovery a serious impact,the formation of difference afterstatistics processing software,P>0.05.Conclusion compared with conventional triple intervention,peptic ulcer patients with Helicobacter pylori positive caused by four means of treatment can significantly improve the eradication rate of Hp,to effectively improve the clinical symptoms of the patients and promote the healing speed,close to two kinds of treatment methods in terms of security,select the corresponding treatment measures according to the specific situation patients,guarantee the treatment effect.%目的 了解幽门螺杆菌(Hp)感染阳性导致出现消化道溃疡患者分别用常规三联、四联疗法进行干预对病情的治疗效果.方法 分析资料选取在2015年——2017年期间在本院接受诊治并确诊Hp阳性消化道溃疡患者相关临床数据,从中选取200例并根据患者所接受治疗方案将其各组100例分为A组(常规三联疗法)和B组(四联疗法).通过对患者临床资料分析后归纳常规三联与四联方案对于Hp阳性消化道溃疡患者的疗效以及安全性差异.结果 A组患者在Hp根除率还有溃疡愈合率方面与B组患者均存在差异,B组更具优越性,组间数据应用统计学软件处理,提示P<0.05;两组患者在接受随访过程中均无严重不良反应事件发生,对疗程后康复无造成严重影响,组建差异经统计学软件处理,提示P>0.05.结论 相对于常规三联干预手段,对于幽门螺杆菌阳性引发的消化道溃疡患者用四联手段进行治疗能明显提升对Hp的根除率,让患者相关临床症状得到有效改善并促进愈合速度,在安全性方面两种治疗手段相接近,根据患者具体情况选择对应治疗措施,保障其治疗效果.

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