Generalized pustular psoriasis of pregnancy (GPPP) is a type of rare and severe pustular psoria-sis. It is clinically characterized by acute eruption of generalized erythema with superficial sterile pustules, which may rapidly coalesce to form lakes of pus. The patient always accompanied by severe systemic symp-toms,such as fever and chills, which can even be life-threatening to mater and fetus. The treatment of GPPP is still challenging, although the mortality has been decreased with the therapy of steroids,cyclosporin,TNF-α antagonists. This article aims to review the update of the etiology, treatment and other aspects of GPPP.%妊娠泛发性脓疱型银屑病(GPPP)是妊娠期发生的一种罕见而严重的脓疱型银屑病。临床以全身急性泛发性红斑，伴浅在性无菌性脓疱为特征，发展迅速，可融合成脓湖，常伴高热、寒战等严重全身症状，甚至危及母胎生命。糖皮质激素、环孢素、TNF－α抑制剂等治疗有一定疗效，可降低GP-PP死亡率。本文从病因、治疗等方面对GPPP研究进展进行概述。
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