目的 研究中医药治疗幽门螺旋杆菌(Hp)感染的用药规律.方法 检索2007年1月～2017年1月中国知网、维普数据库中有关中医药治疗Hp感染的期刊文献,筛选并建立方剂数据库,采用中医传承辅助系统软件进行数据挖掘,对核心药物及其归经、组方规律、核心组合等进行分析.结果 共筛选出治疗Hp感染方剂108首,涉及中药159种,使用频次10次以上的药物共30种.归经分析显示,治疗Hp感染的中药主要归脾、胃二经,其次为肺、肝经.结论 治疗Hp的中药以清热解毒、健脾益气为主.清热解毒药以黄连、蒲公英使用较多,健脾益气药则多用甘草、党参、白术、茯苓、黄芪等.%Objective To study the prescription rule of traditional Chinese medicine (TCM) in the treatment of Helicobacter pylori (I-Ip) infection.Methods The literatures of TCM in the treatment of Hp infection from CNKI and CQVIP were searched from January 2007 to January 2017,the recipe database was screened and set up,the TCM inheritance support system was used to carry out data mining,and the core drugs and its meridian tropism,prescription rules,core combination were analyzed.Results A total of 108 prescriptions about Hp infection were selected,including 159 herbs,and 30 drugs were used for more than 10 times.By analyzing the meridian tropism,TCM for Hp infection were mainly spleen and stomach meridian,followed by lung and liver meridian.Conclusion The Chinese medicine for the treatment of Hp is mainly clearing heat and removing toxicity,strengthening spleen and benefiting qi.The most frequent herbs for clearing heat and removing toxicity are Rhizoma Coptidis,Herba Taraxaci,etc,the most frequent herbs for strengthening spleen and benefiting qi are Radix Glycyrrhizae,Radix Codonopsis,Rhizoma Atractylodis Macrocephalae,Poria,Radix Astragali seu Hedysari,etc.
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