Objective To investigate the influence of TORCH series pathogen infection on pregnancy outcomes of pregnant women in middle and late pregnancy. Methods 846 cases of pregnant women in middle and late pregnancy in our hospital were selected from January 2006 to June 2010. TOX, RV, CMW, and HSV- Ⅱ were detected in the pregnant women. All pregnant women were grouped, on the basis of the detection results. 678 cases of pregnant women with TORCH series pathogene negative were divided into the control group. 168 cases of pregnant women with TORCH series pathogene positive were divided into the observation group. The pregnancy outcomes situation of the two groups were compared respectively. Results The premature rupture of membranes, puerperal disease, dead fetus, fetal distress, stillbirth, neonatal asphyxia, congenital malformation, adverse pregnancy ratio of the observation group were significantly higher than those of the control group (P < 0.05). The premature rupture of membranes, puerperal disease, dead fetus, fetal distress, stillbirth, neonatal asphyxia, congenital malformation, adverse pregnancy ratio of the mixed infection group were significantly higher than those of the single infection group, the differences were statistically significant (P < 0.05). Conclusion TORCH series pathogen infection will have adverse effects on pregnant women in middle and late pregnancy. Detection of TORCH series pathogen for pregnant women in middle and late pregnancy can prevent and control the occurrence of intrauterine fetal infection effectively, which can significantly reduce the incidence of adverse pregnancy. It is worthy of clinical application.%目的 探讨TORCH系列病原体感染对中、晚期孕妇妊娠结局的影响.方法 选取本院2006年1月~2010年6月收治的中、晚期孕妇846例,分别进行弓形虫(TOX)、风疹病毒(RV)、巨细胞(CMW)、单纯疱疹病毒(HSV-Ⅱ)检测,并将所有孕妇进行分组,其中,将TORCH系列病原体呈阴性孕妇678例作为对照组,将TORCH系列病原体呈阳性孕妇168例作为观察组,分别比较各组间妊娠结局情况.结果 观察组在胎膜早破、产褥病、死胎、胎儿宫内窘迫、死产、新生儿窒息、先天性畸形儿、不良妊娠等方面比率均明显高于对照组(P < 0.05);混合感染组在胎膜早破、产褥病、死胎、胎儿宫内窘迫、死产、新生儿窒息、先天性畸形儿、不良妊娠等方面比率均明显高于单一感染组,差异有统计学意义(P < 0.05).结论 TORCH系列病原体感染对中、晚期孕妇妊娠会产生一定程度的不良影响,对中、晚期孕妇进行必要的TORCH系列病原体感染检测可以有效预防和控制胎儿宫内感染的发生,大幅降低不良妊娠的发生率,值得临床推广使用.
展开▼
