Objective To evaluate the mlcroalhuminuria impact of drug therapy in patients with hypertension for exploring more effective clinical treatment. Methods 200 patients with hypertension were randomly divided into two groups, the control group was treated with Valsartan, the treatment group was treated with Valsartan combined with Capiopril. Results After treatment, the SBP, DBF levels between the two groups had significant differences (P < 0.05); and the levels of SBP, DBF in the treatment group were significantly lower than the control group (P < 0.05). After treatment, the urinary microal-buminuiia levels of the two groups were decreased significantly; and which of treatment group was lawer than the control group (P < 0.05). Conclusion Hypertension with microalbuminuria Is quite common, the combination of medications can effectively reduce blood pressure, and reduce the level of urinary microalbuminuria.%目的 探讨药物治疗对高血压患者微量白蛋白尿的影响,为高血压早期肾损害防治探索更有效的临床治疗方法.方法 将200例高血压患者随机分为两组:治疗组与对照组.对照组单独服用缬沙坦治疗,治疗组服用缬沙坦联合卡托普利治疗.结果 治疗后两组收缩压(SBP)、舒张压(DBP)组间均值均显著降低(P<0.05);同时治疗组治疗后的SBP、DBP均值明显少于对照组(P<0.05).两组治疗后的尿微量白蛋白均明显下降,同时治疗组治疗后的尿微量白蛋白水平明显少于对照组(P<0.05).结论 缬沙坦联合卡托普利治疗高血压能在有效降低血压的基础上,降低尿微量白含量.
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