Objective To research the relationship between serum level of vitamin D and allergic rhinitis. Methods 100 children aged from 2 to 6 years old were divided into the experimental group and the control group, each group had 50 cases. Tandem mass spectrometry was used to detect the serum levels of vitamin D. Results Total vitamin D level of control group was (32.87+4.67) ng/mL, vitamin D2 level was (3.84±4.21) ng/mL and vitamin D3 level was (29.96+2.52) ng/mL. Total vitamin D level of experimental group was (23.00±2.00) ng/mL, vitamin D2 level was (3.62±3.04) ng/mL and vitamin D3 level was (20.38+2.32) ng/mL. There were significant differences of total vitamin D level and vitamin D3 level between the two groups (P < 0.05). Conclusion The level of total vitamin D in allergic rhinitis children is lower than that of normal children, with lower level of vitamin D3 primarily.%目的 探讨血清维生素D水平与过敏性鼻炎的相关性.方法 选择海珠区妇幼保健院2～6岁儿童100例,其中健康儿童50例为对照组,患过敏性鼻炎儿童50例为实验组,分别使用串联质谱仪检测其血清维生素D水平.结果对照组总维生素D水平为(32.87±4.67)ng/mL,其中维生素D2水平为(3.84±4.21)ng/mL,维生素D3水平为(29.96±2.52)ng/mL;实验组总维生素D水平(23.00±2.00)ng/mL,其中维生素D2水平(3.62±3.04)ng/mL,维生素D3水平(20.38±2.32)ng/mL.两组总维生素D及维生素D3水平比较差异均存在统计学意义(均P ＜ 0.05).结论 过敏性鼻炎儿童血清维生素D水平比正常儿童偏低,且以维生素D3水平偏低为主.
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