Objective To investigate the clinical effects of hospitalized comprehensive rehabilitation treatment for patients with chronic schizophrenia. Methods 60 patients with chronic schizophrenia hospitalized in our hospital from March 2010 to March 2011 were randomly divided into the observation group and the control group and treated for a period of 6 months. The control group was only given clozapine treatment, without the implementation of hospitalized comprehensive rehabilitation. The observation group was treated with small doses of clozapine and hospitalized comprehensive rehabilitation at the same time. The schizophrenia negative symptom scale (SANS), the brief psychiatric rating scale (BPRS) and the general quality of life inventory-74 (GQOLI-74) were used for assessment before and after treatment. Results For the observation group, the total score and respective score of SANA, BPRS and GQOLJ-74 after treatment were significantly different from those after treatment (P < 0.05). Conclusion Hospitalized comprehensive rehabilitation can significantly improve the negative symptoms of patients with chronic schizophrenia and improve their self care skills in daily living, social activity skills and quality of life.%目的 探讨慢性精神分裂症患者院内综合康复治疗的临床效果.方法 选择我院2010年3月～2011年3月慢性精神分裂症住院患者60例,将上述患者随机分为观察组和对照组,进行为期6个月的治疗.对照组患者仅给予氯氮平治疗,不实施院内综合康复治疗.观察组采用小剂量氯氮平治疗,同时实施院内综合康复治疗.采用分裂症阴性症状量表(SANA)、简明精神病量表(BPRS)和生活质量综合评定问卷74(GQOLI-74)于治疗前后分别进行评定.结果 观察组治疗后SANA、BPRS和GQOLI-74总分及分量表分与治疗前比较差异有统计学意义(P＜0.05).结论 院内综合康复治疗能显著改善慢性精神分裂症住院患者阴性症状,提高其生活自理、社会活动能力和生活质量.
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