目的 探讨亚低温联合依达拉奉治疗急性缺血性脑卒中的的疗效.方法 将82例急性缺血性脑卒中患者随机分为观察组(n = 41)和对照组(n = 41),对照组给予常规治疗,观察组加用亚低温联合依达拉奉治疗.比较治疗前后两组患者神经功能缺损(NIHSS)评分、日常生活活动能力(ADL)评分和预后、血糖、血乳酸及血浆纤维蛋白原(FIB)等变化.结果 观察组的总有效率为95.12%(39/41),显著高于对照组的75.61%(31/41).观察组的NIHSS评分、ADL评分及血糖、血乳酸和FIB的改善情况均明显优于对照组(P ＜ 0.05).结论 亚低温联合依达拉奉治疗急性缺血性脑卒中的近期疗效显著,值得进一步探讨和临床应用.%Objective To investigate the curative effect of moderate hypothermia and Edaravone in the treatment of patients with acute ischemic stroke. Methods 82 cases of acute stroke were randomly divided into control group (n ~ 41) and observation group (n= 41). The control group was only treated with routine drugs, and the observation group was treated with mild hypothermia combined with Edaravone on the base of routine drugs. Before and after treatment, activity of daily living (ADL), national Institutes of health stroke scale (NIHSS), blood sugar, blood lactic acid and plasma fibrinogen (FIB) were e-valuated respectively. Results The overall effective rate of the observation group was 95.12% (39/41), it was significantly higher than 75.61% (31/41) of the control group. NIHSS score, ADL score, blood sugar, blood lactic acid and FIB of the observation group were significantly better than the control group (P ＜ 0.05). Conclusion The recent curative effect is distinct in the treatment of acute ischemic stroke with moderate hypothermia and Edaravone, and It deserves further investlga-rntion and clinical application.
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