目的:观察川芎嗪注射液联合甲钴胺对糖尿病周围神经病变的疗效.方法:将60例糖尿病周围神经病变患者随机分为治疗组和对照组,两组均给于饮食控制及糖尿病基础治疗,治疗组用磷酸川芎嗪注射液,同时口服甲钴胺片0.5 mg,每日3次,4周为1个疗程.对照组口服甲钴胺0.5 mg,每日3次,共4周.结果:治疗组总有效率为93.3%,对照组总有效率为66.7%,两组治疗结果比较差异有高度统计学意义(x2=6.67,P＜0.01).结论:川芎嗪注射液联合甲钴胺能明显缓解糖尿病周围神经病变患者临床症状,提高神经传导速度,治疗糖尿病周围神经病变疗效显著.%Objective: To observe the curative effect of Ligustrazine Injection combined with Mecobalamin in treating diabetic peripheral neuropathy. Methods: Sixty patients with type 2 diabetes and diabetic peripheral neuropathy were randomly divided into treatment group and control group, two groups were given alimentary control and diabetes basis therapy.Patients in treatment group were treated with Ligustrazine Phosphate and Mecobalamin for four weeks, and the patients in control group were treated with Mecobalamin for four weeks. Results: The total effective rate in treatment group was 93.3％, and in control group was 66.7％, the comparison of treatment outcome between two groups had significant difference (x2=6.67,p＜0.01). Conclusion: Ligustrazine Injection combined with Mecobalamin can obviously release clinical symptoms in patients with diabetic peripheral neuropathy, improve nerve conductive velocity, has evident effects in treating diabetic peripheral neuropathy.
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